The article analyzes the documents of state authorities of the first years of Soviet power, which determined the directions of work of higher educational institutions, shows the interpretation and implementation of these decisions of the RSFSR's RSC in Ukraine in the early 20's. Within the article, based on the analysis of the NFU archive documents for 20-30 years th years of the twentieth century. created scientific biographies of the professors of the department Gladky P., Gonchar M., Gordienko V., Domnich K., Zavgorodniy V., Zalipka M., Zaporozhenka M., Zilbera C., Konovalova S., Koshovenko P., Miller L., Nesterenko D., Pogorilii D., Pushkareva F., Stankova A., Radieva V., changes are analyzed in the system of teaching disciplines ideological orientation, the content of these disciplines, teaching methods. Traced changes in the organizational structure of the department change its name.