mixed sequence
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2021 ◽  
Author(s):  
Jing Liu ◽  
Wei Feng ◽  
Chongchong Guo ◽  
Bo Yang ◽  
Lanxi Xiang ◽  
...  

2021 ◽  
Author(s):  
Ananya Paul ◽  
Gregory Man Kai Poon ◽  
Arvind Kumar ◽  
Abdelbasset A. Farahat ◽  
Pu Guo ◽  
...  
Keyword(s):  

2021 ◽  
Author(s):  
Giulia Iadevaia ◽  
Jonathan A. Swain ◽  
Diego Núñez-Villanueva ◽  
Andrew D. Bond ◽  
Christopher A. Hunter

One pot oligomerisation reactions give access to families of oligomers that allow facile analysis of folding propensity and assessment of suitability for sequence-selective duplex formation.


2020 ◽  
Vol 11 (32) ◽  
pp. 8600-8609 ◽  
Author(s):  
Páraic M. Keane ◽  
Kyra O'Sullivan ◽  
Fergus E. Poynton ◽  
Bjørn C. Poulsen ◽  
Igor V. Sazanovich ◽  
...  

Efficient electron transfer requires the complex to be intercalated at a G-C base-pair. Identification of preferred intercalation sites is achieved by TRIR monitoring of the nucleobase vibrations before electron transfer.


2020 ◽  
Vol 18 (24) ◽  
pp. 4645-4655
Author(s):  
Dale C. Guenther ◽  
Raymond G. Emehiser ◽  
Allison Inskeep ◽  
Saswata Karmakar ◽  
Patrick J. Hrdlicka

Invader probes featuring non-nucleotidic bulges are energetically activated for highly specific recognition of complementary double-stranded DNA targets.


2020 ◽  
Vol 18 (1) ◽  
pp. 56-65 ◽  
Author(s):  
Raymond G. Emehiser ◽  
Eric Hall ◽  
Dale C. Guenther ◽  
Saswata Karmakar ◽  
Patrick J. Hrdlicka

Double-stranded (ds) Invader and INA probes allow for efficient and specific recognition of mixed-sequence dsDNA targets, whereas recognition is less efficient and specific with single-stranded LNA-modified DNA strands and fully modified MPγPNAs.


Author(s):  
DongLai Ge ◽  
Junhui Li ◽  
Muhua Zhu ◽  
Shoushan Li

Sequence-to-sequence (seq2seq) approaches formalize Abstract Meaning Representation (AMR) parsing as a translation task from a source sentence to a target AMR graph. However, previous studies generally model a source sentence as a word sequence but ignore the inherent syntactic and semantic information in the sentence. In this paper, we propose two effective approaches to explicitly modeling source syntax and semantics into neural seq2seq AMR parsing. The first approach linearizes source syntactic and semantic structure into a mixed sequence of words, syntactic labels, and semantic labels, while in the second approach we propose a syntactic and semantic structure-aware encoding scheme through a self-attentive model to explicitly capture syntactic and semantic relations between words. Experimental results on an English benchmark dataset show that our two approaches achieve significant improvement of 3.1% and 3.4% F1 scores over a strong seq2seq baseline.


2019 ◽  
Vol 17 (42) ◽  
pp. 9321-9335 ◽  
Author(s):  
Eleni Dimitriou ◽  
Gavin J. Miller

Mixed sequence, C6-hydroxamate-modified alginate disaccharides are prepared using NIS/TMSOTf glycosylation.


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