scholarly journals Programmable approach to convert an “undruggable” DNA target to a “druggable” receptor by mixed-sequence-DNA binding compounds

2021 ◽  
Author(s):  
Ananya Paul ◽  
Gregory Man Kai Poon ◽  
Arvind Kumar ◽  
Abdelbasset A. Farahat ◽  
Pu Guo ◽  
...  
Keyword(s):  
Dna Binding ◽  
Mixed Sequence

scholarly journals Systematic synthetic and biophysical development of mixed sequence DNA binding agents

2017 ◽  
Vol 15 (4) ◽  
pp. 827-835 ◽  
Author(s):  
Ananya Paul ◽  
Arvind Kumar ◽  
Rupesh Nanjunda ◽  
Abdelbasset A. Farahat ◽  
David W. Boykin ◽  
...  
Keyword(s):  
Dna Binding ◽  
Dna Recognition ◽  
Mixed Sequence ◽  
Binding Agents ◽  
Dna Binding Agents

Development of heterocyclic diamidines as programmable molecules for sequence-specific DNA recognition.

Water soluble palladium(ii) and platinum(ii) acyclic diaminocarbene complexes: solution behavior, DNA binding, and antiproliferative activity

2020 ◽  
Vol 44 (15) ◽  
pp. 5762-5773 ◽  
Author(s):  
Tatiyana V. Serebryanskaya ◽  
Mikhail A. Kinzhalov ◽  
Vladimir Bakulev ◽  
Georgii Alekseev ◽  
Anastasiya Andreeva ◽  
...  
Keyword(s):  
Dna Binding ◽  
Antiproliferative Activity ◽  
Water Soluble ◽  
Solution Behavior ◽  
Antitumor Potential ◽  
Acyclic Diaminocarbene

Water soluble Pd(ii) and Pt(ii)–ADC species synthesized via the metal-mediated coupling of isocyanides and 1,2-diaminobenzene have demonstrated antitumor potential.

NMR studies of the R2 repeat and related peptide fragments of the DNA binding domain of c-Myb. New light on the structure and folding of R2.

1999 ◽  
Vol 96 (9/10) ◽  
pp. 1580-1584 ◽  
Author(s):  
I. Ségalas ◽  
S. Desjardins ◽  
H. Oulyadi ◽  
Y. Prigent ◽  
S. Tribouillard ◽  
...  
Keyword(s):  
Dna Binding ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
Peptide Fragments ◽  
Nmr Studies ◽  
Related Peptide

The DNA-binding protein YB-1 is a direct MYCN target and influences repair and resistance in neuroblastoma cell lines

2010 ◽  
Vol 222 (03) ◽  
Author(s):  
S Degen ◽  
S Kuhfittig-Kulle ◽  
JH Schulte ◽  
F Westermann ◽  
A Schramm ◽  
...  
Keyword(s):  
Dna Binding ◽  
Cell Lines ◽  
Binding Protein ◽  
Neuroblastoma Cell ◽  
Dna Binding Protein ◽  
Neuroblastoma Cell Lines
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