Direct and Clean Loading of Nanoparticles into Optical Traps at Millibar Pressures

Nanoparticles levitated by optical fields under vacuum conditions have applications in quantum science, the study of nanothermodynamics and precision sensing. The existing techniques for loading optical traps require ambient conditions and often involve dispersion in liquids, which can contaminate delicate optics and lead to enhanced optical absorption and heating. Here, we present a clean, dry and generic mechanism for directly loading optical traps at pressures down to 1 mbar, exploiting Laser Induced Acoustic Desorption and allowing for the rapid and efficient trapping of nanoparticles.

Development of a miniature time of flight mass spectrometer coupled with an improved substrate-enhanced laser-induced acoustic desorption source (SE-LIAD/TOF-MS)

A novel, compact and sensitive SE-LIAD/TOF-MS has been described. It facilitates the fast sample preparation and a full mass spectrum acquired efficiently and sensitively. More importantly, it features detection of...

Laser-induced acoustic desorption coupled with electrospray ionization mass spectrometry for rapid qualitative and quantitative analysis of glucocorticoids illegally added in creams

We present a strategy for the coupling of laser-induced acoustic desorption (LIAD) with electrospray ionization (ESI) mass spectrometry.