The $$^{27}\hbox {Al}(\hbox {p},\alpha )^{24}\hbox {Mg}$$ reaction at astrophysical energies studied by means of the Trojan Horse Method applied to the $$^2\hbox {H}(^{27}\hbox {Al},\alpha ^{24}\hbox {Mg})\hbox {n}$$ reaction

The $$^{27}\hbox {Al}(\hbox {p},\alpha )^{24}\hbox {Mg}$$ 27 Al ( p , α ) 24 Mg reaction, which drives the destruction of $$^{27}$$ 27 Al and the production of $$^{24}\hbox {Mg}$$ 24 Mg in stellar hydrogen burning, has been investigated via the Trojan Horse Method (THM), by measuring the $$^2\hbox {H}(^{27}\hbox {Al},\alpha ^{24}\hbox {Mg})\hbox {n}$$ 2 H ( 27 Al , α 24 Mg ) n three-body reaction. The experiment covered a broad energy range ($$E_\mathrm{c.m.}\le \,1.5\,\hbox {MeV}$$ E c . m . ≤ 1.5 MeV ), aiming to investigate those of interest for astrophysics. The results confirm the THM as a valuable technique for the experimental study of fusion reactions at very low energies and suggest the presence of a rich pattern of resonances in the energy region close to the Gamow window of stellar hydrogen burning (70–120 keV), with potential impact on astrophysics. To estimate such an impact a second run of the experiment is needed, since the background due the three-body reaction hampered to collect enough data to resolve the resonant structures and extract the reaction rate.

The Trojan Horse Method: A Nuclear Physics Tool for Astrophysics

The Trojan Horse Method (THM) represents an indirect path to determine the bare nucleus astrophysical S-factor for reactions among charged particles at astrophysical energies. This is achieved by measuring the quasi-free cross section of a suitable three-body process. The method is also suited to study neutron-induced reactions, especially in the case of radioactive ion beams. A comprehensive review of the theoretical as well as experimental features behind the THM is presented here. An overview is given of some recent applications to demonstrate the method's practical use for reactions that have a great impact on selected astrophysical scenarios. Expected final online publication date for the Annual Review of Nuclear and Particle Science, Volume 71 is September 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

The role of picornavirus infection in epileptogenesis

Picornaviridae are a family of small positive-strand RNA viruses, and transmitted via the respiratory or fecal-oral route. The neurotropic picornaviruses can induce acute or late recurrent seizures following central nervous system infection, by infecting the peripheral nerve, crossing the blood-brain barrier and migrating in the Trojan-horse method. Theiler’s murine encephalomyelitis virus (TMEV), as a member of Picornaviridae family, can cause encephalitis, leading to chronic spontaneous seizures. TMEV-infected C57BL/6 mice have been used as an animal model for exploring the mechanism of epileptogenesis and assessing new antiepileptic drugs. Astrogliosis, neuronal death and microglial recruitment have been detected in the hippocampus following the picornaviruse-induced encephalitis. The macrophages, monocytes, neutrophils, as well as IL-6 and TNF-α released by them, play an important role in the epileptogenesis. In this review, we summarize the clinical characteristics of picornavirus infection, and the immunopathology involved in the TMEV-induced epilepsy.

Experimental Nuclear Astrophysics With the Light Elements Li, Be and B: A Review

Light elements offer a unique opportunity for studying several astrophysical scenarios from Big Bang Nucleosynthesis to stellar physics. Understanding the stellar abundances of light elements is key to obtaining information on internal stellar structures and mixing phenomena in different evolutionary phases, such as the pre-main-sequence, main-sequence or red-giant branch. In such a case, light elements, i.e., lithium, beryllium and boron, are usually burnt at temperatures of the order of 2–5 × 106 K. Consequently, the astrophysical S(E)-factor and the reaction rate of the nuclear reactions responsible for the burning of such elements must be measured and evaluated at ultra-low energies (between 0 and 10 keV). The Trojan Horse Method (THM) is an experimental technique that allows us to perform this kind of measurements avoiding uncertainties due to the extrapolation and electron screening effects on direct data. A long Trojan Horse Method research program has been devoted to the measurement of light element burning cross sections at astrophysical energies. In addition, dedicated direct measurements have been performed using both in-beam spectroscopy and the activation technique. In this review we will report the details of these experimental measurements and the results in terms of S(E)-factor, reaction rate and electron screening potential. A comparison between astrophysical reaction rates evaluated here and the literature will also be given.