The isomeric ratio (IR) of isomeric pair 109m,gPd, produced in 110Pd(γ, n)109m,gCd reaction and 108Pd(n, γ)109m,gPd neutron capture reactions, induced by thermal, epithermal and mixed thermal-epithermal neutrons have been determined. The off-line activation technique using a spectroscopic system consisting of a HPGe semiconductor detector with high energy resolution and a PC based 8192 channel analyzer (CANBERRA) was applied. The investigated samples were prepared from the 99.99 % purity PdO and irradiated at the electron accelerator Microtron MT-25 of the Joint Institute for Nuclear Research Dubna, Russia. The data analysis and necessary corrections were made to upgrade the precision of the experimental method. The obtained results were discussed, compared and combined with those from other authors to point out the role of the reaction channels in nuclear reactions.