Ethnobotanical review of Medicinal Plants Used against Diarrhea and Dysentery in Northeastern India (Assam)

Background: Since primitive times, plants have been extensively utilized in conventional remedies for primary health care. It is observed that medicinal plants have various bioactive components. It becomes an alternative choice for synthetic medications to treat diarrhea and dysentery, which are the primary waterborne diseases with high mortality rates that bring substantial health threats to global populations. Objective: The present review aims to look over the ethnobotanical knowledge for the treatment of diarrhea and dysentery and folklore practices by the people prevailing in Assam. Methods: In this perspective, an extensive literature survey was carried out to understand the mechanism, control, and treatment of diarrhea and dysentery in different online academic databases and books. An advanced search was carried out in 'PubMed' and 'Google Scholar' using the term "Phytoconstituents" and "antidiarrheal" along with "Phytoconstituents" and "anti-amoebic". Results: Data retrieved from databases were analyzed and interpreted to conclude that in Assam, diarrhea and dysentery are the primary leading causes of mortality among children under five years. It is mainly due to the unhygienic livelihood, unavailability of safe drinking water, unhealthy food, seasonal rainfall, flood, and open defecation. The present investigations reveal that the people of Assam use 39 plant species belonging to 36 families to cure diarrhea and dysentery. Conclusion: The present study established the effective use of medicinal plants by various communities in Assam to treat diarrhea and dysentery. Furthermore, it can be used to develop a new therapeutic approach to create new chemical entities (NCE) in drug discovery, which are safe, fruitful, and inexpensive.

Evolution of seafloor pockmarks along the Northern Orange Basin, Offshore South Africa: Interplay between fluid flow and bottom current activities

Pockmarks are pervasive geomorphologic features identified along continental margins resulting from fluid expulsion on the seafloor. However, the understanding of the underlying geological mechanism/control in relation to their evolution, distribution, and morphology is limited, especially along data-starved continental margins such as the Northern Orange Basin. Analysis of a high-quality 3D seismic reflection data reveals at least 50 individual pockmarks, two channel-like depressions and several irregular depressions in water depth ranging between 800 m and 2400 m. Morphologically, the pockmarks are circular, elongated, comet-like and crescentic in shape, with diameters and depths ranging between ∼0.2 - 2.8 km and ∼10 - 130 m, respectively. Preferential alignment of these pockmarks on the seafloor in relation to the axis of underlying turbidite channels, erosional morphologies and mass transport complexes portray a genetic relationship. The slope architecture hints at the possibility of both deep and shallow fluid source driving pockmark formation. Under this scenario, deep thermogenic gas derived from Cretaceous source rocks migrated along fault systems associated with the Late Cretaceous Megaslide complex to the overburden. The fluids are stored/redistributed in contourite and turbidite channels and subsequently focused toward the seafloor under an increased pore pressure regime. Yet, the fluids may be either solely biogenic gas or heterogeneous, incorporating biogenic components and pore-water derived from the channels and dewatering of the contourites. Importantly, the discovery of crescentic and elongated end-member pockmark morphologies indicate post-formation sculpting of the initial pockmark morphologies by bottom currents. The discovery of these deep-water pockmarks opens the possibility that such fluid escape features may be more widespread than currently documented in the Northern Orange Basin. This has implications in understanding of the petroleum system here and their potential role in the South Atlantic marine ecosystems and global climate change in terms of the expulsion of climate forcing gases.

Design and Research of Intelligent Safety Monitoring Robot for Coal Mine Shaft Construction

This study analyzes the main causes of accidents in the period of coal mine shaft construction and the shortage of the existing safety monitoring technology, puts forward the intelligent safety monitoring robot technology based on shaft construction, and deeply investigates the functions that the safety monitoring robot should have. Besides, the research objective of intelligent safety monitoring robot for shaft construction is pointed out, and the research is carried out from such aspects as the robot body structure, walking mechanism, adsorption mechanism, control, communication, intelligent sensing, hazard source recognition, recognition of explosive detonators, and software platform development. As well, this study designs the technical device of intelligent safety monitoring robot for shaft construction, defines the characteristics of this technology, expounds the important significance of studying this technology, and indicates the development trend of this technology.