Biocompatibility and Antibiofilm Properties of Samarium Doped Hydroxyapatite Coatings: An In Vitro Study

The implant-related infection as a consequence of bacterial adherence and biofilm formation remains one of the main causes of implant failure. Grace to recent advances in materials science, their great mechanical properties and their biocompatibility (both in vitro and in vivo), antibacterial coatings have gradually become a primary component of the global strategy for preventing microbial colonization. In the present work, novel antibacterial coatings containing hydroxyapatite nanoparticles doped with two different concentrations of samarium (5SmHAp and 10SmHAp) were obtained on Si substrates using the dip coating method. The morphology and physicochemical properties of these modified surfaces were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). In addition, their antimicrobial effects and biocompatibility were assessed. The results showed a continuous and homogeneous layer, uniformly deposited, with no cracks or impurities. 5SmHAp and 10SmHAp surfaces exhibited significant antibiofilm activity and good biocompatibility without inducing cytotoxic effects in human gingival fibroblasts. All these findings indicate that samarium doped hydroxyapatite coatings could be great candidates for the development of new antimicrobial strategies.

Preparation of Silver Antibacterial Agents with Different Forms and Their Effects on the Properties of Water-Based Primer on Tilia europaea Surface

Micron silver particles prepared by the chemical reduction method, urea formaldehyde resin-coated nano-silver solution microcapsules, and nano-silver solution were used as three kinds of antibacterial agents. These were added to a water-based primer on the surface of Tilia europaea in contents of 1.0%, 4.0%, 7.0%, 10.0%, 13.0%, and 16.0%. In order to achieve the best comprehensive performance of the water-based primer, the mechanical, optical, and antibacterial properties of the three antibacterial coatings with different contents of silver antibacterial agents were explored. It was concluded that when the antibacterial agent content was 4.0%, the color difference, impact resistance, adhesion, and gloss of water-based primer on the Tilia europaea surface were better. When the antibacterial agent content added was 16.0%, the antibacterial properties of the three groups of coatings improved to 94.89%, 81.75%, and 83.98%, respectively. The results provide a research idea for the preparation of antibacterial coatings on the surface of wood furniture.