Giant breast fibroadenoma in pregnancy

Overview Objective: To present unusual case of rapidly growing breast fibroadenoma during pregnancy. Case report: Breast fibroadenomas are hormone-dependent tumors which can grow rapidly during pregnancy. We present a case of giant fibroadenoma, first detected before pregnancy, which grew rapidly under the influence of pregnancy hormones and was excised in the third trimester. Conclusion: Fibroadenomas are benign breast lesions in young women. They are hormone-dependent tumors, which can grow rapidly especially during pregnancy and/ or lactation and imitate malignancy. In each case of a newly created breast lesion, it is necessary to proceed responsibly to the clinical examination, which is a base for further decision concerning the necessity of taking a bio­psy for histological verification. Keywords: breast fibroadenoma – pregnancy – lactation – phyllodes tumor

Giant fibroadenoma of the breast: a benign breast mass mimicking malignancy

Fibroadenoma is a common benign lesion of the breast that usually occurs in young females. Giant fibroadenoma of the breast is a rare benign pathology, which is defined as fibroadenoma greater than 5 cm in size and/or weighs more than 500 g. It is usually found in adolescent women. A 37-year-old woman undergoing treatment for infertility was referred to the breast clinic with an ulcerating left breast lump that had progressively increased in size. Examination showed a fungating left breast mass that obliterated the nipple-areola complex. Ultrasound showed a large soft tissue mass in the left breast with enlarged left axillary lymph nodes. Computed tomographic (CT) scan showed a 13×17 cm left breast mass. Core biopsy of this mass reported possibility of phyllodes tumor, while axillary fine-needle aspiration cytology (FNAC) showed no evidence of malignancy. Total mastectomy with immediate reconstruction using silicone implant was performed. Final histopathology reported giant fibroadenoma. Most cases on giant fibroadenoma reported in literature are limited to adolescent or young females, however, our patient was relatively old, which makes this a rare case.

Giant fibroadenoma mimicking phylloides tumor in post-menopausal female: a case report and review of literature

Giant fibroadenomas are rare breast lesions in elderly women especially post-menopausal women and accounting for 0.5-2% of all cases of fibroadenomas. They pose diagnostic as well as therapeutic challenge because resemblance of its clinical and imaging features with other breast lesions, especially phylloides tumor. We present a rare case of giant fibroadenoma of breast in postmenopausal female of 53 year of age mimicking phylloides tumor. Ultrasonography and fine needle aspiration cytology (FNAC) suggestive of fibroadenoma. Tumor was completely excised and diagnosis of giant fibroadenoma was confirmed by histopathology. Breast conserving surgery is the gold standard treatment.

JUVENILE GIANT FIBROADENOMA: A CASE REPORT

Giant juvenile fibroadenomas are rare variants of fibroadenoma, usually occurring in girls between the ages of 10 and 18 years. They are characterized by massive and rapid enlargement of a rubbery, mobile, and non-tender mass. The etiology is not well understood and believed to be an increased sensitivity to normal estrogen level. We report a case of giant juvenile fibroadenoma in a 17 years old girl that was managed by surgical excision with conservation of normal breast tissue, nipple, and areola.

Oncoplastic Approach to Giant Benign Breast Tumors Presenting as Unilateral Macromastia

Benign breast tumors attaining large size constitute an important cause of unilateral macromastia. Their usual treatment involves enucleation or excision with a margin based on pathology and waiting for spontaneous retraction of skin envelope. In very large tumors, this will leave the residual breast deflated and unaesthetic, with spontaneous skin retraction giving unpredictable results. Application of the principles of oncoplastic surgery are helpful in this situation. Here, we present two cases of benign giant tumors—a giant fibroadenoma and a giant lipoma—managed by reduction mammaplasty approach to restore the breast symmetry and aesthetics.