Plutonium in Manhattan Project workers: Using autopsy data to evaluate organ content and dose estimates based on urine bioassay with implications for radiation epidemiology

Purpose Radiation dose estimates in epidemiology typically rely on intake predictions based on urine bioassay measurements. The purpose of this article is to compare the conventional dosimetric estimates for radiation epidemiology with the estimates based on additional post-mortem tissue radiochemical analysis results. Methods The comparison was performed on a unique group of 11 former Manhattan Project nuclear workers, who worked with plutonium in the 1940s, and voluntarily donated their bodies to the United States Transuranium and Uranium Registries. Results Post-mortem organ activities were predicted using different sets of urine data and compared to measured activities. Use of urinalysis data collected during the exposure periods overestimated the systemic (liver+skeleton) deposition of 239Pu by 155±134%, while the average bias from using post-exposure urinalyses was –4±50%. Committed effective doses estimated using early urine data differed from the best estimate by, on average, 196±193%; inclusion of follow-up urine measurements in analyses decreased the mean bias to 0.6±36.3%. Cumulative absorbed doses for the liver, red marrow, bone surface, and brain were calculated for the actual commitment period. Conclusion On average, post-exposure urine bioassay results were in good agreement with post-mortem tissue analyses and were more reliable than results of urine bioassays collected during the exposure.

Narrative and nuclear weapons politics: the entelechial force of the nuclear origin myth

This paper contributes a novel way to theorise the power of narratives of nuclear weapons politics through Kenneth Burke's concept of entelechy: the means of stating a things essence through narrating its beginning or end. The paper argues that the Manhattan Project functions narratively in nuclear discourse as an origin myth, so that the repeated telling of atomic creation over time frames the possibilities of nuclear politics today. By linking Burke's work on entelechy with literature on narrative and eschatology, the paper develops a theoretical grounding for understanding the interconnection of the nuclear past, present, and future. The paper supports its argument by conducting a wide-ranging survey of academic and popular accounts of the development of the atomic weapon in the US Manhattan Project. It reveals a dominant narrative across these accounts that contains three core tropes: the nuclear weapon as the inevitable and perfected culmination of humankind's tendency towards violence; the Manhattan Project as a race against time; and the nuclear weapon as a product of a fetishized masculine brilliance.