AbstractAs we interact with our surroundings, we encounter the same or similar objects from different perspectives and are compelled to generalize. For example, we recognize dog barks as a distinct class of sound, despite the variety of individual barks. While we have some understanding of how generalization is done along a single stimulus dimension, such as frequency or color, natural stimuli are identifiable by a combination of dimensions. To understand perception, measuring the interaction across stimulus dimensions is essential. For example, when identifying a sound, does our brain focus on a specific dimension or a combination, such as its frequency and duration? Furthermore, does the relative relevance of each dimension reflect its contribution to the natural sensory environment? Using a 2-dimension discrimination task for mice we tested untrained generalization across several pairs of auditory dimensions. We uncovered a perceptual hierarchy over the tested dimensions that was dominated by the sound’s spectral composition. A model tuned to the predictability inherent in natural sounds best explained the behavioral results, suggesting that the perceptual hierarchy parallels the predictive content of natural sounds.