multiple crossovers
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2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Daichi Oka ◽  
Yasushi Hirose ◽  
Shoichiro Nakao ◽  
Tomoteru Fukumura ◽  
Tetsuya Hasegawa

AbstractAnderson localization derived from randomness plays a crucial role in various kinds of phase transitions. Although treated as a free variable parameter in theory, randomness in electronic materials is hard to control experimentally owing to the coexisting Coulomb interaction. Here we demonstrate that the intrinsic anion disorder in a mixed-anion system of SrNbO2N induces a significant random potential that overwhelms the Coulomb potential while maintaining the lattice structure. A metal-to-insulator transition is triggered by a chemical modulation of the electron density where the critical electron density is more than three orders of magnitude greater than that predicted by the well-known Mott criterion. The localized electrons show characteristic electrical properties such as temperature-dependent multiple crossovers of conduction mechanisms and a positive magnetoresistance above 50% at low temperature. The large magnetoresistance is attributed to wave-function shrinkage of the localized states and clearly visualizes the anisotropy in the band structure, which indicates a compatibility of the periodicity and randomness.


2020 ◽  
Vol 224 ◽  
pp. 01012
Author(s):  
V Kobak ◽  
A Zhukovskiy ◽  
V Porksheyan ◽  
A Kuzin

The article deals with the problem of inhomogeneous minimax problem solution, what is typical of scheduling theory. This problem is NPcomplete, and there is no exact algorithm for it, which has a polynomial time for large-scale problems. Therefore a quick algorithm that gets approximate tables is used. A possible method for solving this problem is considered a hybrid model, representing the synthesis of two genetic algorithms models, namely models Goldberg and CGS. Goldberg’s model is viewed from multiple crossovers and most promising mutation. As it is difficult to make calculations analytically and often impossible to make it in practice, the computational experiment was carried out in this article. The results of the experiment are described in the tables, which graphically show a comparison of the hybrid model effectiveness. The comparison is based on the accuracy results obtained for two types of crossovers with the basic parameters of genetic algorithm. It is proved that the use of hybrid algorithm leads to the results which are more précised to the optimal ones, despite the deterioration in the temporary search characteristics solutions.


2018 ◽  
Vol 97 (4) ◽  
Author(s):  
O. Nájera ◽  
M. Civelli ◽  
V. Dobrosavljević ◽  
M. J. Rozenberg

2006 ◽  
Vol 74 (11) ◽  
Author(s):  
M. Kindermann ◽  
P. W. Brouwer

2005 ◽  
Vol 187 (12) ◽  
pp. 4116-4126 ◽  
Author(s):  
Gustavo Santoyo ◽  
Jaime M. Martínez-Salazar ◽  
César Rodríguez ◽  
David Romero

ABSTRACT Gene conversion has been defined as the nonreciprocal transfer of information between homologous sequences. Despite its broad interest for genome evolution, the occurrence of this mechanism in bacteria has been difficult to ascertain due to the possible occurrence of multiple crossover events that would mimic gene conversion. In this work, we employ a novel system, based on cointegrate formation, to isolate gene conversion events associated with crossovers in the nitrogen-fixing bacterium Rhizobium etli. In this system, selection is applied only for cointegrate formation, with gene conversions being detected as unselected events. This minimizes the likelihood of multiple crossovers. To track the extent and architecture of gene conversions, evenly spaced nucleotide changes were made in one of the nitrogenase structural genes (nifH), introducing unique sites for different restriction endonucleases. Our results show that (i) crossover events were almost invariably accompanied by a gene conversion event occurring nearby; (ii) gene conversion events ranged in size from 150 bp to 800 bp; (iii) gene conversion events displayed a strong bias, favoring the preservation of incoming sequences; (iv) even small amounts of sequence divergence had a strong effect on recombination frequency; and (v) the MutS mismatch repair system plays an important role in determining the length of gene conversion segments. A detailed analysis of the architecture of the conversion events suggests that multiple crossovers are an unlikely alternative for their generation. Our results are better explained as the product of true gene conversions occurring under the double-strand break repair model for recombination.


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