definitive screening
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Materials ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 5787
Author(s):  
Leejon Choy ◽  
Seungkyung Kim ◽  
Jeonghun Park ◽  
Myungchang Kang ◽  
Dongwon Jung

Recently, friction stir welding of dissimilar materials has emerged as one of the most significant issues in lightweight, eco-friendly bonding technology. In this study, we welded the torsion beam shaft—an automobile chassis component—with cast aluminum to lighten it. The study rapidly and economically investigated the effects of friction stir welding and process parameters for A357 cast aluminum and FB590 high-strength steel; 14 decomposition experiments were conducted using a definitive screening design that could simultaneously determine the effects of multiple factors. Friction stir welding experiments were conducted using an optical microscope to investigate the tensile shear load behavior in the welding zone. In addition to understanding the interactions between tool penetration depth and plunge speed and tool penetration depth and dwell time, we investigated and found that tool penetration depth positively affected the size of the hooking area and contributed to the stabilization and size reduction of the cavity. The experimental results showed that the plunge depth and tool penetration depth effects were most important; in this case, the plunge depth negatively affected the magnitude of tensile shear load, whereas the tool penetration depth had a positive effect. Therefore, when selecting a tool, it is important to consider the plunge depth and tool penetration depth in lap welding.


Molecules ◽  
2021 ◽  
Vol 26 (16) ◽  
pp. 5048
Author(s):  
Maha S. Elsayed ◽  
Noha M. Eldadamony ◽  
Salma S. T. Alrdahe ◽  
WesamEldin I. A. Saber

Generally, the bioconversion of lignocellulolytics into a new biomolecule is carried out through two or more steps. The current study used one-step bioprocessing of date palm fronds (DPF) into citric acid as a natural product, using a pioneer strain of Trichodermaharzianum (PWN6) that has been selected from six tested isolates based on the highest organic acid (OA) productivity (195.41 µmol/g), with the lowest amount of the released glucose. Trichoderma sp. PWN6 was morphologically and molecularly identified, and the GenBank accession number was MW78912.1. Both definitive screening design (DSD) and artificial neural network (ANN) were applied, for the first time, for modeling the bioconversion process of DPF. Although both models are capable of making accurate predictions, the ANN model outperforms the DSD model in terms of OA production, as ANN is characterized by a higher value of R2 (0.963) and validation R2 (0.967), and lower values of the RMSE (13.44), MDA (11.06), and SSE (9749.5). Citric acid was the only identified OA as was confirmed by GC-MS and UPLC, with a total of 1.5%. In conclusion, DPF together with T. harzianum PWN6 is considered an excellent new combination for citric acid biosynthesis, after modeling with artificial intelligence procedure.


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