collagen microsphere
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Author(s):  
Chunrong Yang ◽  
Huazhong Wu ◽  
Jianhua Wang

AbstractThe objective of this study was to investigate the therapeutic potential of nano-bioglass/phosphatidylserine/collagen (nBG/PS/COL) scaffolds loaded with steroidal saponins as an inducer factor for skeletal defects. The drugs-encapsulated bone substitute was prepared by loading steroidal saponins-collagen microsphere suspension in nano-bioglass and phosphatidylserine (PS) composite. The scaffolds possess an interconnected porous structure with a porosity of about 82.3%. The pore size ranges from several micrometers up to about 400 μm. The drug release assays showed the long-term sustained release of steroidal saponins from the scaffolds with effective and safe bioactivity. Moreover,


2015 ◽  
Vol 221 (4) ◽  
pp. e117 ◽  
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Ope A. Asanbe ◽  
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Lab on a Chip ◽  
2012 ◽  
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pp. 3277 ◽  
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