In this paper, we give a general inertial Krasnoselskii–Mann algorithm for solving inclusion problems in Banach Spaces. First, we establish a weak convergence in real uniformly convex and q-uniformly smooth Banach spaces for finding fixed points of nonexpansive mappings. Then, a strong convergence is obtained for the inertial generalized forward-backward splitting method for the inclusion. Our results extend many recent and related results obtained in real Hilbert spaces.