Analyzing the Association between Pattern and Returns Using Goodman–Kruskal Prediction Error Reduction Index (λ)

For selecting and interpreting appropriate behaviour of proportion between buy/neutral/sell patterns and high/moderate/low returns, the prediction error reduction index is a very useful tool. It is operationally interpretable in terms of the proportional reduction in error of estimation. We first obtain the buy/sell pattern using an Optimal Band. The analysis of the association between patterns and returns is based on the Goodman–Kruskal prediction error reduction index ( λ ). Empirical analysis suggests that the prediction of returns from patterns is more impressive or of less error as compared to the prediction of patterns from returns. We demonstrated the prediction index for Index NIFTY 50, BANK-NIFTY, and NIFTY-IT of NSE (National Stock Exchange), for the period 2010–2020.

Efek pemberian pakan berlebih berupa limbah sayuran pakcoy terhadap daya cerna, tingkat penurunan limbah, dan kandungan protein pada lalat tentara hitam (Hermetia illucens (Linnaeus))

One of the recent organic waste management programs actively developed is organic waste bioconversion by using larvae of black soldier fly (Hermetia illucens (Linnaeus)). However, one major challenge in organic waste management in Indonesia is the limited space to manage the wastes at waste collection centers. This condition increases the number of wastes to be converted (consumed) by larvae of soldier fly. In this study, the condition was imitated in the laboratory where larvae were individually fed with a large number of wastes. Larvae were divided into 4 groups and were fed with 200, 300, 400, and 500 mg/larva/day of rotten vegetable waste (Pakcoy) and were replicated 3 times. Variables observed during the study were the growth rate, consumption capability, level of waste reduction (waste reduction index, WRI), consumption efficiency (efficiency of conversion of digested-feed, ECD), the weight of harvested biomass, and protein content of larvae, pupae, and adults. The results showed that there was no significant correlation between the weight of harvested biomass and the amount of substrate provided to larvae (one-way ANOVA, P > 0.05). The increasing amount of substrate reduced the efficiency of waste reduction and consumption (one-way ANOVA, P < 0.05). This study also showed that the possible upper limit of consumption capability of larvae was 400 mg/larva/day. On the other hand, the increasing amount of substrate increased the protein content of biomass of each developmental stage.

Sound Reduction of Ventilation Ducts through Walls: Experimental Results and Updated Models

Ventilation ducts can have a negative effect on the sound reduction index between two rooms if they pass through the dividing structure without treatments. The overall sound reduction of a ventilation duct is dependent on several factors including the transmission loss when sound is breaking in and out from the duct. This study aims to model the sound reduction of a combined system with a separating wall and a ventilation duct through it. Three walls, characterized according to ISO 717-1, are combined with three different ventilation ducts, two circular and one rectangular with different dimensions. Laboratory measurement data are used to determine the sound reduction of the different configurations and the type of treatments needed for each configuration. A proposed model with existing theory for describing sound transmission losses of circular and rectangular ventilation ducts predicts the shape of the measurement data for many frequency bands. A new theory part is developed through an iterative process for circular ducts, which is based on measurements with previous methods and studies as a guide because the existing prediction scheme is somewhat perplexing. For rectangular ducts, the existing theory has been updated to better match measurement data. The application of the proposed theory and model in this article shows similar results when compared to measurements. The difference in weighted sound reduction index between developed theories and measurement data is 0–1 dB for every configuration.

Perforated Steel Stud to Improve the Acoustic Insulation of Drywall Partitions

Steel studs are an inevitable part of drywall construction as they are lightweight and offer the required structural stability. However, the studs act as sound bridges between the plasterboards, reducing the overall sound insulation of the wall. Overcoming this often calls for wider cavity walls and complex stud decoupling fixtures that increase the installation cost while reducing the floor area. As an alternative approach, this research reveals the potential of perforated studs to improve the acoustic insulation of drywall partitions. The acoustic and structural performance is characterized using a validated finite element model that acted as a prediction tool in reducing the number of physical tests required. The results established that an acoustic numerical model featuring fluid-structure-interaction can predict the weighted sound reduction index of a stud wall assembly at an accuracy of ±1 dB. The model was used to analyze six perforated stud designs and found them to outperform the sound insulation of non-perforated drywall partitions by reducing the sound bridging. Overall, the best performing perforated stud design was found to offer improvements in acoustic insulation of up to 4 dB, while being structurally compliant.

Optimization of organic waste processing using Black Soldier Fly larvae Case study: Diponegoro university

Waste that is not handled correctly can cause problems for humans and the environment. Therefore, proper waste management efforts are needed to solve this waste problem. One method of processing organic waste is the use of Black Soldier Fly (BSF) larvae. Larvae BSF can degrade organic waste, and the life cycle of BSF acts as a decomposer. This study examines BSF larvae’s ability to decompose biodegradable organic waste, especially for banana waste, cucumber waste, and food waste in the Diponegoro University environment, and to decide the effect of the variable type of food. The frequency of feeding carried out on the growth rate of BSF larvae and to choose the decomposition results of biodegradable organic waste carried out by BSF larvae. This research method is carried out by comparing the effectiveness of waste degradation by BFS with EM4. The value of significance in degrading waste is obtained from the calculation of the Waste Reduction Index, or it can be called WRI. The analysis results show that the WRI value in waste processing using BFS is more significant than in waste processing using EM4. That concludes that BSF fly larvae (Hermetia illucens) effectively reduce organic waste compared to EM4.

Perforated Steel Stud to Improve the Acoustic Insulation of Drywall Partitions

Steels studs are an inevitable part of drywall construction as they are lightweight and offer the required structural stability. However, the studs act as sound bridges between the plasterboards reducing the overall sound insulation of the wall. Overcoming this often calls for wider cavity walls and complex stud decoupling fixtures that increase the installation cost while reducing the floor area. As an alternative approach, this research reveals the potential of perforated studs to improve the acoustic insulation of drywall partitions. The acoustic and structural performance is characterized using a validated finite element model that acted as a prediction tool in reducing the number of physical tests required. The results established that an acoustic numerical model featuring fluid-structure-interaction can predict the weighted sound reduction index of a stud wall assembly at an accuracy of &plusmn;1 dB. The model was used to analyze six perforated stud designs and found to outperform the sound insulation of non-perforated drywall partitions by reducing the sound bridging. Overall, the best performing perforated stud design was found to offer improvements in acoustic insulation of up to 4 dB, while being structurally compliant.

Harmine Augments the Cytotoxic and Anti-invasive Potential of Temozolomide Against Glioblastoma Multiforme Cells

Background: Glioblastoma multiforme (GBM) is considered the deadliest human cancer. Temozolomide is now a part of postresection standard chemotherapy for this type of cancer. Unfortunately, resistance to temozolomide is a major obstacle to treatment success. Combination therapy with natural anticancer agents increases the activity of temozolomide against cancer cells. Objectives: This study aimed to assess the effects of temozolomide in combination with harmine against GBM cells. Methods: Cancer cells were treated with temozolomide and/or harmine. After 24, 48, 72, and 96 h, the viability of the cells was assessed by the MTT test. The combination index and dose reduction index were determined by CompuSyn software. Tumor invasion potential was investigated by evaluating cell migration, invasion, and adhesion. The real-time PCR technique was done to study the expression pattern of two genes involved in cancer cell invasion. Statistical analysis was performed using one-way analysis of variance and Tukey’s post-hoc test, and differences were considered non-significant at P > 0.05. Results: After treatment with temozolomide, cell viability showed a concentration- and time-dependent decrease, and the cells’ survival rate decreased. The combination of temozolomide and harmine had a synergistic effect. Also, temozolomide and/or harmine treatment decreased cancer cells’ migration, invasion, and adhesion potentials, as well as the expression of metalloproteinases 2 and 9 in T98G cells. Conclusions: The combination of temozolomide and harmine can be promising for the successful treatment of GBM.

Effect of Finely Ground Limestone and Dolomite on Compression Strength and Reduction Swelling of Vanadium-Titanium Pellets

Vanadium−titanium magnetite (VTM) is an important raw material for ironmaking under the situation of increasingly demanding scarce resources. To further improve the metallurgical properties of pellets, and to satisfy the requirements of blast furnace slag basicity, finely ground dolomite and limestone have been added to the pellet. In this study, the effect of finely ground dolomite and limestone on the metallurgical properties (green pellet drop strength, cold compression strength, reduction swelling index, and microscopic mineral structure) of VTM pellets were investigated. With the addition of finely ground dolomite and limestone, the drop strength of the green pellet was improved. The effect of adding finely ground limestone was greater than adding finely ground dolomite. Adding more finely ground dolomite and limestone compared to pellets without limestone and dolomite, the cold compression strength was decreased, which was attributed to the decomposition of limestone and dolomite during the induration of pellets. With the addition of dolomite, the reduction swelling index (RSI) increased firstly and then decreased. When the basicity of the pellet was 0.54 to 0.94, the slag phase with the lowest melting point was formed, corresponding to the maximum of the reduction swelling index. For the pellets with added limestone, the reduction swelling of the pellets deteriorated. The reduction index of the pellets increased and reached the maximum (26.6%) at a basicity of 1.54, which belongs to abnormal swelling.