This chapter reviews the journal submission and review process, starting with navigating manuscript submission sites and proceeding through editorial review, peer review, editorial decisions, revising and resubmitting manuscripts, developing reviewer response letters, finalizing manuscripts, and correcting publisher proofs. The chapter provides an in-depth tutorial on responding to reviewer requests, prioritizing which requests to respond to first, how to respond to different editorial styles, and how to use the response letter to “push back” against reviewer requests without being combative. The chapter also offers suggestions for handling conflicting reviewer requests, requests for new analyses, and how to revise a paper when new analyses change the message or take away previously significant findings.