Digital screens are everywhere. The world of textbooks becomes vibrant, challenging, interesting, and filled with various global opportunities and tremendous risks. Open textbooks are used for reading, digital literacy, visual literacy, and multimedia. They are incorporated into a variety of learning environments. It is a real need for new psychopedagogical models based on adaptive learning. But, what open textbooks are in need to be developed for success? This chapter explores the shifting perspectives of learning with open textbooks and concludes with the need for future research in adaptivity and interactivity. It analyzes the concepts of affordability, adaptivity, feasibility, open learning, open science, open culture, and open learning environment in order to outline the scientific framework of the metasystems learning design theory. The conclusion is provided at the end.