The word issues derived from Latin exire, “to go out,” “to go forth,” embraces meanings that include “outflows,” “problems,” and “extensions.” The figuration of death flows into contrasting figurations of life and light, and light extends to its use specifically in analogies of vision and being: Fiat lux. Poiesis, “making, producing, creating,” is fundamental to insight in the sign systems of mathematics and verbal language, both of which use analogy constructively. Traditionally, analogy is the connector between the known and the unknown, the sensible and the infinite, this earth and what is beyond it. The first three chapters of this book treat evil, sin, and death in Spenser, Donne, and Milton, and these treatments open into questions of mortalism, individuation, self-knowledge, and the means by which we represent and consider them. Chapter 4 turns to the history and theory of analogy, and subsequent chapters examine analogy, light, and death in the science and poetry of Kepler, Donne, and Milton.