Correlation between glycated hemoglobin HbA1c and serum lipid profile in patients with type 2 diabetes

Background: Hyperlipidemia is a common risk factor for diabetes that leads to cardiovascular disease, one of the causes of death of diabetic patients. Theaimof this study was to investigate the association between HbA1c levels and serum lipids in Libyan patients withtype 2 diabetes. Material and methods: The study was conducted in 2019 on 325 patients (174 males, 151 females) with type 2 diabetes referred to a private clinical laboratory in Tripoli, Libya. Blood samples were collected for measurement of HbA1c, fasting blood glucose and serum lipid concentrations. Diabetes was defined according to the American Diabetes Association criteria.The data were analyzed using an independent t-test and Pearson’scorrelation test.Results: The ages of the patients ranged from 40 to 83 years, with a mean of 51.52 ± 14.32 years SD. No significant correlation between HbA1c and age was noted (r=0.011, p=0.063). There was a significant positive correlation betweenHbA1c level and fasting blood glucose (r =0.641, p=0.000), low-density lipoprotein (r = 0.240, p = 0.000), total cholesterol (r = 0.223, p = 0.000) and triglycerides(r=0.140,p 0.067). The correlation between HbA1c and high-density lipoprotein-C was negative but not significant (r= -0.088, p = 0.123). Conclusion: HbA1c could be used as a predictor of dyslipidemia and thus it may serve as anindicator of the development of cardiovascular disease in patients with type-2 diabetes mellitus.

Prevalence of Iron Deficiency Anemia Among Pregnant Women in Zawia, Libya

Background: anemia is the most nutritional disorders affecting pregnant women particularly iron deficiency anemia IDA.IDA threatened the mother islife and considered as an established risk factor for intrauterine growth retardation, leading on too poor neonatal health and perinatal death. Objective: the aim of the study was to estimate the prevalence of IDA in Zawia city according to their hemoglobin level, age, and education. Methods and materials: the study was carried out in different centers in Zawia city, it was comprised 82 pregnant women aged 19-42 years, at various stage of pregnancy, out of 82 women 54 fulfilled the criteria, pregnant women who weren’t have known about their hemoglobin, they were excluded. The data collected by using of a questioner including 30 questions were asked to participants face to face. Data analysis: after the date is collected it classified and analyzed to determine the percentage of pregnant women suffering from iron deficiency anemia. The data analyzed by using of Microsoft excel (2013). Results: the prevalence of anemia in the present study was 85.18%, This prevalence was almost consistent with studies conducted in ZAWIA city over the last years, from the current study it is evidence that pregnant women had poor knowledge regarding main risk of IDA as well as poor practices for IDA prevention.

Libyan Journal of Medical Research (LJMR): Moving to the Next Step

The Editor-in-Chief and executive editors are grateful to all previous editors and editorial board members who have served in any volume since the beginning of the journal. Their exemplary dedication and hard work have been the driving forces behind the Journal's success and punctuality over the last 14 years. Libyan Journal of Medical Research (LJMR) advances to the next stage today. It is healthy and necessary to pause and reflect on one's accomplishments and deficiencies, especially at various stages and milestones.

Intraluminal duodenal “windsock” diverticulum; Case Report and discussion

Intraluminal duodenal diverticulum (IDD) is a rare developmental anomaly usually found in the second portion of the duodenum. The cause appears to be a failure of recanalization of the occluded foregut lumen of the human embryo, resulting in a fenestrated mucosal membrane [1]. A small aperture in this diaphragm will gradually cause it to elongate caudally in response to duodenal peristalsis to form the so called “wind-sock” configuration. Symptoms are nonspecific and generally depend on the degree of duodenal obstruction; 25% of cases are associated with GI bleeding. In most documented cases, IDD was diagnosed radiologically, but the value of endoscopy for diagnosis and treatment has been amply demonstrated.