HEMOGLOBIN THIOLS: BIOLOGICAL SIGNIFICANCE AND REGULATION

Human hemoglobin has two reactive cysteines (Cys-93β) located on the surface of the molecule. Inclusion of these thiols in the composition of dinitrosyl iron complexe is one way of regulating their reactivity. The thiols bound into complexes exhibit enhanced reactivity with electrophiles and are protected from oxidation by tert-butyl hydroperoxide.

PROSPECTS FOR THE USE OF CHAT-BOT IN THE TREATMENT OF ANOMALIES OF THE MAXILLOFACIAL REGION

The article discusses the possibilities of using modern information technologies, in particular chatbot, in dentistry in the treatment of patients with congenital malformations of the facial skeleton. In order to im-prove the awareness of both doctors and parents at all stages of receiving medical care and rehabilitation.

LOCAL ABDOMINAL HYPOTHERMIA APPARATUS

The article is discussed of the new method of the local abdominal hypothermia by using elements Peltier in patient with peritonitis.

CHANGES IN FINE STRUCTURE OF ADRENAL CHROMAFFIN CELLS AFTER DEVELOPMENTAL EXPOSURE TO ENDOCRINE DISRUPTER DDT

Developmental exposure to low doses of endocrine disrupter DDT results in negative changes in fine structure and impaired functional activity of adrenal chromaffin cells.

SILVER NANOPARTICLES USING FOR PROCESSING SUTURE MATERIAL

The method of modifying suture material with silver nanoparticles was tested. The paper presents the results nanoparticle sorption on the surface of different types of polymer fibers. The expediency of processing suture threads for intraoperative prophylaxis of purulent-septic complications in surgery is shown.

TRANSCRIPTIONAL REGULATION OF ADRENAL CORTEX POSTNATAL DEVELOPMENT AND FUNCTION

Expression of transcriptional factor Oct4 and Shh in rat adrenal cortex during postnatal development and the role for this factors in functional activity of adrenal cortex and tissue homeostasis was determined.

OBJECTIVE ASSESSMENT OF FISH QUALITY IN THE STORAGE PROCESS USING NMR SPECTROSCOPY

The article discusses the problem of an objective assessment of the quality of chilled and frozen fish during storage. The NMR method is recommended for a comprehensive analysis of changes in the metabolic profile of cod and Pacific chum salmon during refrigerated storage.

GAS TRANSMITTER CYCLES IN THE MAMMAL ORGANISM

The proposed concept of the cyclic organization of gas transmitters allows us to answer the question: how do living organisms provide regulation and stabilization of these physiologically active compounds involved in intracellular and intercellular signaling.

PROSPECTS FOR PREVENTION AND REHABILITATION IN ARTERIAL HYPERTENSION

The effect of rehabilitative non-drug methods on the normalization of blood pressure was studied in 33 study participants. A theoretical analysis of the causes of arterial hypertension was carried out. A hypothesis has been formed on the role of the nervous system in the development of hypertension.

ALTERED PROLIFERATION OF THYMIC LYMPHOCYTES IN PUBERTAL RATS EXPOSED TO LOW DOSES OF DDT

Low-dose developmental exposure to DDT alters proliferative activity of thymic lymphocytes of rats. Higher proliferation rate and low differentiated lymphoblast content are found in rat thymus during puberty.