<p>Non-contact physiological monitoring has garnered interest in the<br />research community. However, studies employ different imaging<br />system configuration, including illuminant profile and wavelength,<br />camera type and frame rate, and distance to the skin. In this paper,<br />we propose an easily customizable imaging system for evaluating<br />physiological monitoring parameters. The system’s design allows<br />plug-and-play compatibility with various illumination sources,<br />camera types, lenses, and optical components. Results using one<br />configuration shows the feasibility of spatial blood perfusion analysis<br />using this imaging system, where areas exhibiting clean blood<br />pulsatility can be identified at the surface level.</p>