Second-generation PFBC combined cycle plants introduce additional dimensions of operational and configurational considerations over their first generation counterparts. With the capability to raise gas turbine inlet temperatures to state of the art and beyond, the second-generation systems introduce a matrix of parameters that require in-depth analysis before the plant design point can be determined. The interactions among turbine inlet temperature, turbine exhaust temperature, excess-air level, steam conditions, steam cycle participation, PFBC operating temperature, and the configuration of the heat recovery apparatus produce a myriad of possible combined-cycle plant configurations. This paper provides insight into how these parameters interact and how the correct selection of the parametric values can produce various plants of best efficiency, highest output, and simplest configuration.