Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis

Chapter 11 Detection and characterization of highly polar metabolites by lc-ms: proper selection of lc column and use of stable isotope-labeled drug to study metabolism of ribavirin in rats

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80013-4 ◽

2005 ◽

pp. 277-293 ◽

Cited By ~ 4

Author(s):

S.K. Chowdhury ◽

VS. Gopaul ◽

N. Blumenkrantz ◽

R. Zhong ◽

K.M. Kulmatycki ◽

...

Keyword(s):

Stable Isotope ◽

Proper Selection ◽

Polar Metabolites ◽

Selection Of

Download Full-text

Preface

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80001-8 ◽

2005 ◽

pp. v-vi

Author(s):

Swapan K. Chowdhury

Download Full-text

Chapter 7 The utility of in vitro screening for the assessment of electrophilic metabolite formation early in drug discovery using hplc-ms/ms

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80009-2 ◽

2005 ◽

pp. 159-182

Author(s):

Diane E. Grotz ◽

Nigel A. Clarke ◽

Kathleen A. Cox

Keyword(s):

Drug Discovery ◽

In Vitro Screening ◽

Metabolite Formation

Download Full-text

Chapter 1 LC-MS and drug metabolism: A journey back in time, present trends and future directions

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80003-1 ◽

2005 ◽

pp. 1-5

Author(s):

Kevin B. Alton

Keyword(s):

Drug Metabolism ◽

Future Directions

Download Full-text

Chapter 12 Cytochrome p450 (cyp) and udp-glucuronosyltransferase (ugt) enzymes: role in drug metabolism, polymorphism, and identification of their involvement in drug metabolism

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80014-6 ◽

2005 ◽

pp. 295-336 ◽

Cited By ~ 2

Author(s):

Anima Ghosal ◽

Ragulan Ramanathan ◽

Narendra S. Kishnani ◽

Swapan K. Chowdhury ◽

Kevin B. Alton

Keyword(s):

Cytochrome P450 ◽

Drug Metabolism ◽

Udp Glucuronosyltransferase

Download Full-text

Chapter 3 Commonly encountered analytical problems and their solutions in liquid chromatography/ tandem mass spectrometry (LC/MS/MS) methods used in drug development

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80005-5 ◽

2005 ◽

pp. 35-64 ◽

Cited By ~ 2

Author(s):

Japan K. Majumdar

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Drug Development ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Chapter 10 Oxidative metabolites of drugs and xenobiotics: lc-ms methods to identify and characterize in biological matrices

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80012-2 ◽

2005 ◽

pp. 225-276 ◽

Cited By ~ 4

Author(s):

Ragulan Ramanathan ◽

Swapan K. Chowdhury ◽

Kevin B. Alton

Keyword(s):

Biological Matrices ◽

Oxidative Metabolites

Download Full-text

Subject index

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80015-8 ◽

2005 ◽

pp. 337-338

Download Full-text

Chapter 2 Strategies for increasing throughput for pk samples in a drug discovery environment

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80004-3 ◽

2005 ◽

pp. 7-34 ◽

Cited By ~ 2

Author(s):

Walter A. Korfmacher

Keyword(s):

Drug Discovery

Download Full-text

Chapter 5 In vitro dmpk screening in drug discovery, role of lc-ms/ms

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis ◽

10.1016/s1464-3456(05)80007-9 ◽

2005 ◽

pp. 105-122 ◽

Cited By ~ 2

Author(s):

Inhou Chu ◽

Amin A. Nomeir

Keyword(s):

Drug Discovery

Download Full-text

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis
Latest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Elsevier

Chapter 11 Detection and characterization of highly polar metabolites by lc-ms: proper selection of lc column and use of stable isotope-labeled drug to study metabolism of ribavirin in rats

Preface

Chapter 7 The utility of in vitro screening for the assessment of electrophilic metabolite formation early in drug discovery using hplc-ms/ms

Chapter 1 LC-MS and drug metabolism: A journey back in time, present trends and future directions

Chapter 12 Cytochrome p450 (cyp) and udp-glucuronosyltransferase (ugt) enzymes: role in drug metabolism, polymorphism, and identification of their involvement in drug metabolism

Chapter 3 Commonly encountered analytical problems and their solutions in liquid chromatography/ tandem mass spectrometry (LC/MS/MS) methods used in drug development

Chapter 10 Oxidative metabolites of drugs and xenobiotics: lc-ms methods to identify and characterize in biological matrices

Subject index

Chapter 2 Strategies for increasing throughput for pk samples in a drug discovery environment

Chapter 5 In vitro dmpk screening in drug discovery, role of lc-ms/ms

Export Citation Format

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical AnalysisLatest Publications

TOTAL DOCUMENTS

H-INDEX

Published By Elsevier

Chapter 11 Detection and characterization of highly polar metabolites by lc-ms: proper selection of lc column and use of stable isotope-labeled drug to study metabolism of ribavirin in rats

Preface

Chapter 7 The utility of in vitro screening for the assessment of electrophilic metabolite formation early in drug discovery using hplc-ms/ms

Chapter 1 LC-MS and drug metabolism: A journey back in time, present trends and future directions

Chapter 12 Cytochrome p450 (cyp) and udp-glucuronosyltransferase (ugt) enzymes: role in drug metabolism, polymorphism, and identification of their involvement in drug metabolism

Chapter 3 Commonly encountered analytical problems and their solutions in liquid chromatography/ tandem mass spectrometry (LC/MS/MS) methods used in drug development

Chapter 10 Oxidative metabolites of drugs and xenobiotics: lc-ms methods to identify and characterize in biological matrices

Subject index

Chapter 2 Strategies for increasing throughput for pk samples in a drug discovery environment

Chapter 5 In vitro dmpk screening in drug discovery, role of lc-ms/ms

Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS - Progress in Pharmaceutical and Biomedical Analysis
Latest Publications