scholarly journals Heritability Analysis of Spherical Equivalent, Axial Length, Corneal Curvature, and Anterior Chamber Depth in the Beaver Dam Eye Study

2009 ◽  
Vol 127 (5) ◽  
pp. 649 ◽  
Author(s):  
Alison P. Klein
Author(s):  
Feride Tuncer Orhan ◽  
Haluk Huseyin Gürsoy

Aim To evaluate consecutive measurements of the biometric parameters, age, and refraction error in a Turkish population at primary school age. Materials and Methods A total of 197 children aged between 7-12 years were included. The data of three consecutive measurements of children, who were examined at least once a year for three years using both cycloplegic auto-refractometry and optical biometry, were used in this retrospective study. Spherical equivalent <-0.50D was considered to be myopic; >+0.75D was considered to be hypermetropic. Age, gender, body mass index, spherical equivalent, axial length, anterior chamber depth, central corneal thickness, keratometry, and lens thickness were analyzed. The onset data obtained in 2013 whereas, the final data were from 2015. Logistic and Cox regression analyses were performed (p<0.05). Results The mean of the onset and the final spherical equivalents were 0.19D (0.56), and 0.08D (0.80), respectively. The myopia prevalence was increased among refractive errors in observation periods (univariable analysis p=0.029; multivariable analysis p=0.017). The onset axial length (HR:4.55, 95%CI:2.87-7.24, p<0.001), keratometry (HR:2.04, 95%CI:1.55-2.67, p<0.001) and age (HR:0.73, 95%CI: 0.57-0.92, p=0.009) correlated myopia progression. To calculate the estimated spherical equivalent, the onset data were included in the logistic regression model. The onset data of spherical equivalent (β=0.916, p<0.001), axial length (β=-0.451, p<0.001), anterior chamber depth (β=0.430, p=0.005) and keratometry (β=-0.172, p<0.001) were found to be significantly associated with the mean SE at the final data. Conclusions To calculate the estimated spherical equivalent following three years, an equation was proposed. The estimated refractive error of children can be calculated by using the proposed equation with the associated onset optical parameters.


2020 ◽  
Author(s):  
MANDEFRO SINTAYEHU KASSA ◽  
GIRUM W GESSESSE

Abstract Background : The main objective of the study was to report on the main parameters of ocular biometry and Intra ocular lens power of patients attending a cataract surgical program in Eastern Ethiopia. Methods : The study was a cross sectional study on 765 eyes which were legible for cataract surgery during a mass eye camp conducted from April 04 to April 10, 2018 at Bisidimo Hospital,Eastern Ethiopia.Ocular biometric parameters such as axial length (AL), anterior chamber depth (ACD), mean corneal curvature (MCC) were measured using automated keratorefractometer(Retinomax) and Sonomed A - Scan. Analysis of variance and multivariate analysis were done to determine association of ocular biometry components with socio demography of the study subjects. Results : A total of 765 eyes were enrolled in this study. The mean corneal curvature and the mean anterior chamber depth were found to be 7.61 mm and 2.88mm respectively. The mean axial length was estimated to be 22.98 mm. The mean refractive power of Intra ocular lenses was calculated to be 19.34D. The mean axial length in females was shorter than that of males by 0.24 and this was statistically significant ( P - value = 0.01). Under multiple linear regression model gender had a statistically significant impact on the axial length. The mean Anterior chamber depth in males was also larger than that of females by nearly 0.1 and this was statistically significant (P - value = 0.001). Under multiple linear regression model both age and gender had a statistically significant impact on the anterior chamber depth. There was no a statistically significant difference on the mean Intra ocular lens power required for male and female patients.Conclusion : This study is the first of its kind to provide a larger population based normative data on the most important parameters of ocular biometry in Ethiopia.The female sex was a strong predictor of small axial length and shallow anterior chamber. Increasing age had no effect on the axial length but was found to be a stronger predictor of shallow anterior chamber. Key words : Axial length, Anterior chamber depth, Corneal curvature, Intra ocular lens.


2017 ◽  
Vol 178 ◽  
pp. 58-64 ◽  
Author(s):  
Mehdi Shajari ◽  
Carla Cremonese ◽  
Kerstin Petermann ◽  
Pankaj Singh ◽  
Michael Müller ◽  
...  

Author(s):  
Raja A. M. ◽  
Rajendraprasad A. ◽  
Seema G.

Background: To find out whether there is a correlation between intra ocular pressure and ocular biometric values like corneal curvature, anterior chamber depth, lens thickness and vitreous chamber depth in myopic eyes.Methods: A cross sectional clinical study was conducted in karuna medical college hospital Palakkad Kerala, India from September 2015 to August 2017. 1000 eyes of 500 myopic patients attending the ophthalmology OPD were included in this study. Goldman applanation tonometry was used to measure intra ocular pressure. Bausch and Lomb keratometer was used to measure corneal curvature and Biometer A scan machine was used to measure anterior chamber depth, lens thickness, vitreous chamber depth and axial length.Results: In this study majority of the patients age group was 16-20 years. The overall mean intra ocular pressure was 15mmhg and mean radius of corneal curvature was 44.12D. In this study average anterior chamber depth was 3.55mm and mean lens thickness was 3.56mm.Mean vitreous chamber depth was 18.40. In this study mean axial length was 24.60mm.Conclusions: Amount of myopia and variation in corneal curvature was not statistically significant. There was no correlation between intra ocular pressure and degree of myopia. But anterior chamber depth, lens thickness, vitreous chamber depth and axial length were statistically very significant with amount of myopia.


2019 ◽  
Vol 7 (24) ◽  
pp. 4283-4286
Author(s):  
Hien Thi Thu Nguyen ◽  
Dung Thi Thanh Nguyen ◽  
Dong Ngoc Pham ◽  
Anh Phuong Tran ◽  
Do Quyet ◽  
...  

BACKGROUND: Myopia is most prevalent type of refraction error. In some Asian countries, the prevalence of myopia can be 80 – 90% in the population aged 17 – 18. AIM: To analyze the correlation between ocular biometric indices and refraction status in Vietnamese young myopes. METHODS: A prospective cross – section study was conducted in young myopes. Data on axial length, central cornea thickness, corneal topography & anterior chamber depth and spherical equivalent were collected. Independent Sample T Test and ANOVA test were used to compare between groups. The correlations between ocular biometry and myopic spherical equivalent refraction were examined by Pearson Correlation with the level of significance p < 0.05. RESULTS: Totally, 418 eyes from 209 patients were recruited. The average axial length, central cornea thickness, cornea refraction & anterior chamber depth were 25.68 ± 1.09 mm, 539.78 ± 32.665 µm, 43.16 ± 1.369 D, 3.30 ± 0.243 mm, respectively. The correlation between axial length and spherical equivalent refraction (SER) was high (r = - 0.742, p < 0.0001) while those between central cornea thickness and cornea refraction were negligible (r = - 0.107, p = 0.029; r = -0.123, p = 0.012; respectively). There was no correlation between anterior chamber depth and spherical equivalent refraction (r = 0.019, p = 0.697). CONCLUSION: Among ocular biometric indices, axial length was significantly correlated with spherical equivalent of young adult patients.


2020 ◽  
pp. 112067212090203
Author(s):  
Tetsuya Muto ◽  
Shigeki Machida

Purpose: To clarify the chronological changes in the anterior chamber structure and identify the spherical equivalent and axial length to assess the effects of steroid pulse treatment in patients with Vogt–Koyanagi–Harada disease with active uveitis. Methods: The anterior chamber condition, including anterior chamber volume, central anterior chamber depth, peripheral anterior chamber depth, anterior chamber angle, and pupil diameter, was measured using Pentacam, and axial length was measured using IOLMaster in patients with Vogt–Koyanagi–Harada disease between June 2015 and February 2018. Furthermore, the best-corrected visual acuity, spherical equivalent, and retinal foveola thickness were also analyzed. All patients were treated with steroid pulse. All these factors were compared before and at 1 and 6 months of treatment. Results: Significant changes were observed in the anterior chamber volume, central anterior chamber depth, peripheral anterior chamber depth, anterior chamber angle, axial length, best-corrected visual acuity, spherical equivalent, and retinal foveal thickness before and at 1 and 6 months of steroid pulse treatment ( P < 0.001, P < 0.001, P < 0.001, P = 0.0015, P = 0.027, P < 0.001, P = 0.0043, and P < 0.001, respectively). No significant difference was observed in the pupil diameter before and at 1 month and 6 months of steroid pulse treatment ( P = 0.11). Conclusion: The anterior chamber structure, axial length, best-corrected visual acuity, spherical equivalent, and retinal foveal thickness were dramatically changed by steroid pulse treatment in patients with Vogt–Koyanagi–Harada disease who develop active uveitis. These changes were completed within 1 month.


1970 ◽  
Vol 3 (2) ◽  
pp. 155-158
Author(s):  
M Gupta ◽  
RR Sukul ◽  
Y Gupta ◽  
M Dey ◽  
A Phougat ◽  
...  

Aim: To study the various ocular anatomical and physiological parameters in presbyopia. Materials and methods: We studied the various ocular anatomical and physiological parameters like corneal curvature (keratometry readings: K1 and K2), central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT) and axial length (AL) in 100 presbyopic patients between 35 - 55 years of age. The patients were divided into two age groups: I (35 – 44 years) and II (45-55 yrs). ACD, AL and LT were measured using an Ascan. CCT was measured with ultrasonic pachymetry. Results: The CCT decreased (BE), LT increased and ACD decreased (RE) significantly with increasing age (p < 0.05). There was no significant difference in males and females. Nearly 3/4th of the total increase in lens thickness was responsible for the decrease in the anterior chamber depth and the rest, 1/4th , goes posteriorly. Corneal curvature and AL showed no significant change with age. Conclusions: The mean of CCT decreased significantly with advancing age. As age increased, the mean value of lens thickness increased and anterior chamber depth decreased. Nearly 3/ 4th of total increase in LT was anteriorly, decreasing the ACD. Corneal curvature and AL has no relation with age. Key words: Presbyopia, central corneal thickness, anterior chamber depth, lens thickness, axial length DOI: http://dx.doi.org/10.3126/nepjoph.v3i2.5269 Nepal J Ophthalmol 2011; 3(2): 155-158


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