Characterization of DSM-III-R Criteria for Uncomplicated Alcohol Withdrawal Provides an Empirical Basis for DSM-IV

1991 ◽  
Vol 48 (5) ◽  
pp. 442 ◽  
Author(s):  
Edward M. Sellers
2019 ◽  
Vol 80 (3) ◽  
pp. 319-330 ◽  
Author(s):  
Leslie A. Brick ◽  
Lauren Micalizzi ◽  
Valerie S. Knopik ◽  
Rohan H. C. Palmer

Author(s):  
John C. Markowitz

This chapter undertakes a review of the diagnosis of posttraumatic stress disorder (PTSD), as defined in the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-IV and DSM5). It recounts the controversy over what constitutes a DSM Criterion A “trauma,” as opposed to other upsetting events. The chapter distinguishes between acute and chronic trauma, age of trauma, and other facets of traumatic events. It emphasizes interpersonal aspects of trauma. The chapter discusses the use of assessment instruments for serial measurement of PTSD and related symptoms. It further addresses the IPT characterization of PTSD as a treatable medical illness that is not the patient’s fault.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
G. Martinotti ◽  
M. Di Nicola ◽  
D. Tedeschi ◽  
A. Frustaci ◽  
R. De Filippis ◽  
...  

Introduction:In this multicenter, randomised, single-blind, parellel group, comparison trial we aimed to investigate the efficacy of lorazepam, tiapride and pregabalin in alcohol withdrawal. Craving and psychiatric symptoms improvements were the secondary endpoints.Methods:One-hundred-nine alcohol dependent subjects (DSM-IV) were detoxified and subsequently randomised into three groups, respectively receiving 200-400 mg of tiapride (TIA; mean dosage 300 mg), 2-5 mg of lorazepam (LOR; mean dosage 3 mg) and 150-450 mg of pregabalin (PRE; mean dosage 280 mg). Withdrawal symptomatology was determined by the Clinical Institute Withdrawal Assessment for Alcohol (CIWA-Ar), whereas the level of craving for alcohol was evaluated by a 10-cm Visual Analogue Scale (VAS) and the Italian -version of the Obsessive and Compulsive Drinking Scale (OCDS). Psychiatric symptomatology was evaluated by the Symptom Check List 90 Revised (SCL-90 R).Results:All the three medications have shown efficacy on reducing alcohol drinking indices, craving scores and withdrawal symptomatology. The reduction observed in the PRE group was significantly higher than those in the LOR and TIA groups. In terms of safety and tolerability, all the compounds were generally well-tolerated. Only one patient has reported an epileptic episode during the treatment with tiapride.Discussion:Results from this study globally place the three medications at the same range of efficacy, with the PRE group reporting an higher reduction of withdrawal symptoms. Another point in favour of the employment of pregabalin was represented by a better outcome in those patients reporting a comorbid psychiatric disorder.


CNS Spectrums ◽  
2017 ◽  
Vol 23 (4) ◽  
pp. 271-277 ◽  
Author(s):  
Bernardo Dell’Osso ◽  
Matteo Vismara ◽  
Cristina Dobrea ◽  
Laura Cremaschi ◽  
Benedetta Grancini ◽  
...  

IntroductionBipolar disorder (BD) is a chronic, highly disabling condition associated with psychiatric/medical comorbidity and substantive morbidity, mortality, and suicide risks. In prior reports, varying parameters have been associated with suicide risk.ObjectivesTo evaluate sociodemographic and clinical variables characterizing Italian individuals with BD with versus without prior suicide attempt (PSA).MethodsA sample of 362 Italian patients categorized as BD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM IV-TR) was assessed and divided in 2 subgroups: with and without PSA. Sociodemographic and clinical variables were compared between prior attempters and non-attempters using corrected multivariate analysis of variance (MANOVA).ResultsMore than one-fourth of BD patients (26.2%) had a PSA, with approximately one-third (31%) of these having>1 PSA. Depressive polarity at onset, higher number of psychiatric hospitalizations, comorbid alcohol abuse, comorbid eating disorders, and psychiatric poly-comorbidity were significantly more frequent (p<.05) in patients with versus without PSA. Additionally, treatment with lithium, polypharmacotherapy (≥4 current drugs) and previous psychosocial rehabilitation were significantly more often present in patients with versus without PSA.ConclusionsWe found several clinical variables associated with PSA in BD patients. Even though these retrospective findings did not address causality, they could be clinically relevant to better understanding suicidal behavior in BD and adopting proper strategies to prevent suicide in higher risk patients.


2021 ◽  
Vol 111 (6) ◽  
pp. 209-220
Author(s):  
Lucia Cinato

The translation of multilingual texts, in which diatopic, diastratic and diaphasic varieties contribute to the characterization of the figures and their milieus, poses the problem of the sociolinguistic adequacy of the translation. It is well known that the greatest challenge lies in the varieties caused by the spatial variation of the language, since it is practically impossible to establish perfect equivalence between dialects. However, the reproduction of diamesic varieties, in particular the written reproduction of the spoken language, can cause great difficulties for translators. The article presents the TRADIVARIO project, the aim of which is to investigate strategies and tendencies in the translation of multilingual literary texts for the German-Italian language pair that are characterized by a pronounced sociolinguistic stratification or representative of the variety structure of the spoken language of the present. In addition, the concrete goal of the project is the creation of a parallel corpus as well as the development of a digital platform, which makes the results of the investigation researchable and which can serve as a tool both for translators and learners and as an empirical basis for contrastive linguistic research.


2021 ◽  
Vol 54 (1-2) ◽  
pp. 69-86
Author(s):  
Teja Furlan ◽  
Monika Kavalir

The paper uses keyword analysis as the empirical basis for the characterization of Shakespeare’s character Iago from Othello, the Moor of Venice. The aim of the paper is to determine how Iago’s manner of speech reflects his deceitful and manipulative nature and how it differs from the speech-styles of non-deceitful prominent characters: Othello, Cassio, Roderigo, Desdemona and Emilia. Keywords for the chosen characters are based on the corpora of character speech and the Sketch Engine tool is used to process the data. The results are then interpreted and discussed on the basis of six interconnected points of discussion: focus, adjectives, use of the expression Moor, references to the handkerchief, poisoning-the-ears technique, and pronouns, all of which confirm that Iago’s manipulative nature is indeed evident in his speech and that there is a clear difference between his speech-style and the speech-styles of other, non-deceitful, prominent characters.


Author(s):  
B. L. Soloff ◽  
T. A. Rado

Mycobacteriophage R1 was originally isolated from a lysogenic culture of M. butyricum. The virus was propagated on a leucine-requiring derivative of M. smegmatis, 607 leu−, isolated by nitrosoguanidine mutagenesis of typestrain ATCC 607. Growth was accomplished in a minimal medium containing glycerol and glucose as carbon source and enriched by the addition of 80 μg/ ml L-leucine. Bacteria in early logarithmic growth phase were infected with virus at a multiplicity of 5, and incubated with aeration for 8 hours. The partially lysed suspension was diluted 1:10 in growth medium and incubated for a further 8 hours. This permitted stationary phase cells to re-enter logarithmic growth and resulted in complete lysis of the culture.


Author(s):  
A.R. Pelton ◽  
A.F. Marshall ◽  
Y.S. Lee

Amorphous materials are of current interest due to their desirable mechanical, electrical and magnetic properties. Furthermore, crystallizing amorphous alloys provides an avenue for discerning sequential and competitive phases thus allowing access to otherwise inaccessible crystalline structures. Previous studies have shown the benefits of using AEM to determine crystal structures and compositions of partially crystallized alloys. The present paper will discuss the AEM characterization of crystallized Cu-Ti and Ni-Ti amorphous films.Cu60Ti40: The amorphous alloy Cu60Ti40, when continuously heated, forms a simple intermediate, macrocrystalline phase which then transforms to the ordered, equilibrium Cu3Ti2 phase. However, contrary to what one would expect from kinetic considerations, isothermal annealing below the isochronal crystallization temperature results in direct nucleation and growth of Cu3Ti2 from the amorphous matrix.


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