Prehabilitation versus no prehabilitation to improve functional capacity, reduce postoperative complications and improve quality of life in colorectal cancer surgery

Abstract Background: Colorectal surgery is reported to have significant effects on patients, both physically and psychologically. On other hand, infections are found to be a major risk factor in Sudan and Sub-Saharan Africa such as intestinal Schistosoma colitis, especially those presenting with sigmoid colonic adenocarcinoma.Aim of the study: To assess the quality of life of patients after colorectal cancer surgery and the effect of the stoma on their life.Methods: A descriptive cross-sectional hospital-based study was done at Soba University Hospital. A sample of 72 patients with colorectal cancer who had undergone colorectal surgery was fully covered and interviewed using the SF-36 Quality of life standard questionnaire.Results: The total sample was 72 with a mean age of 51.1 ± 14.6 years. 79% were married, 70% were working, with free business being the most encountered occupation (36.1%). However, only 48.6% were still employed at the time of surgery. Regarding the mental health component, there was a significant difference in social functioning domain mean scores between patients who were employed and unemployed patients. Where the physical functioning and role physical domains were found to differ significantly with the different educational attainment of patients. Patients who did not undergo radiation therapy reported higher mean scores of role limitation due to physical problems, compared to patients who received radiation therapy.Conclusion: Our result found the quality of life was affected negatively in terms of the level of pain and presence of colostomy with sexual activity affection but the other parameters were not strongly affected.

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THE ROLE OF BIOLOGICAL MARKERS IN THE DIAGNOSIS OF POSTOPERATIVE INFECTIONS IN COLORECTAL CANCER SURGERY (review)

Koloproktologia ◽

10.33878/2073-7556-2019-18-3-105-118 ◽

2019 ◽

Vol 18 (3(69)) ◽

pp. 105-118

Author(s):

S. I. Achkasov ◽

M. A. Sukhina ◽

A. I. Moskalev ◽

E. N. Nabiev

Keyword(s):

Colorectal Cancer ◽

Postoperative Complications ◽

Biological Markers ◽

Infectious Complications ◽

Cancer Surgery ◽

Postoperative Infections ◽

Colorectal Cancer Surgery ◽

Free Survival

Infectious complications in colorectal cancer surgery is one of the major problems in postoperative complications structure. The frequency of the latter is 5-22%, and in 5-20% of cases such complications lead to death. It should be noted that the development of postoperative complications leads to a decrease in the quality of life of patients, general and relapse-free survival of patients operated on for colorectal cancer. One of the promising ways to diagnose postoperative infectious complications after surgery is to assess the level of biological markers of plasma inflammation. It can be used to identify patients with a high probability of infection and be an indication for earlier additional methods of diagnosing complications. Currently, biomarkers that are used for early postoperative infection detection include increase in the leukocytes level in peripheral blood, CRP, PCT, CD64 neutrophils and others. Despite the large number of studies, the question of the role of these biomarkers in postoperative infections diagnosis in the patients who under went colorectal cancer surgery remains unclear.

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The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients

Aging & Mental Health ◽

10.1080/13607863.2020.1725807 ◽

2020 ◽

pp. 1-10

Author(s):

Ties L. Janssen ◽

Jolanda de Vries ◽

Paul Lodder ◽

Miriam C. Faes ◽

Gwan H. Ho ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Depressive Symptoms ◽

Cognitive Functioning ◽

Older Patients ◽

Postoperative Delirium ◽

Cancer Surgery ◽

Colorectal Cancer Surgery

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Evaluation of a Post-Operative Rehabilitation Program in Patients Undergoing Laparoscopic Colorectal Cancer Surgery: A Pilot Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18115632 ◽

2021 ◽

Vol 18 (11) ◽

pp. 5632

Author(s):

Sveva Maria Nusca ◽

Attilio Parisi ◽

Paolo Mercantini ◽

Marcello Gasparrini ◽

Francesco Antonio Pitasi ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Pilot Study ◽

Exercise Program ◽

Cancer Surgery ◽

Colorectal Cancer Surgery ◽

End Of Treatment ◽

Eortc Qlq C30 ◽

Eortc Qlq

This pilot study explores the effects of a post-operative physical exercise program on the quality of life (QoL) and functional and nutritional parameters of patients that underwent laparoscopic colorectal cancer surgery, compared to usual care alone. The intervention group (IG) attended a 2-month-long supervised and combined exercise–training program during the post-operative period. Both IG and control group (CG) participated in the QoL, functional, and nutritional assessments before exercise training (T0), 2 months after the beginning of the exercise (end of treatment) (T1), and 2 (T2) and 4 (T3) months from the end of treatment. Eleven patients with colorectal cancer that underwent laparoscopic surgery were enrolled (six intervention; five control). The IG showed significant improvements compared to the CG in “Physical functioning” (PF2) (p = 0.030), “Cognitive functioning” (CF) (p = 0.018), and “Fatigue” (FA) (p = 0.017) of the European Organization for Research and Treatment of Cancer Quality of Life-C30 Questionnaire (EORTC QLQ-C30) at T1; in SMWT (p = 0.022) at T1; in PF2 (p = 0.018) and FA (p = 0.045) of EORTC QLQ-C30 at T2, in phase angle (PhA) of bioelectrical impedance analysis (p = 0.022) at T3. This pilot study shows that a post-operative, combined, and supervised physical exercise program may have positive effects in improving the QoL, functional capacity, and nutritional status in patients that undergo laparoscopic colorectal cancer surgery.

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