scholarly journals The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion

2017 ◽  
Vol 11 (6) ◽  
pp. 655-669 ◽  
Author(s):  
Anup Sharma ◽  
Janet Mendonca ◽  
James Ying ◽  
Hea-Soo Kim ◽  
James E. Verdone ◽  
...  
Keyword(s):  
Cell Motility ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene

EP300-A miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas

2009 ◽  
Vol 126 (1) ◽  
pp. 114-124 ◽  
Author(s):  
Soeren Torge Mees ◽  
Wolf Arif Mardin ◽  
Claudia Wendel ◽  
Nicole Baeumer ◽  
Edith Willscher ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene

scholarly journals Clinical and pathological significance of Homo sapiens ceramide synthase 2 (CerS-2) in diverse human cancers

2019 ◽  
Vol 39 (5) ◽  
Author(s):  
Qian Zhang ◽  
Jin-yan Wang ◽  
Wei Yan ◽  
Dan-dan Wang ◽  
Su-jin Yang ◽  
...  
Keyword(s):  
Tumor Metastasis ◽  
Therapeutic Strategy ◽  
Malignant Tumors ◽  
Homo Sapiens ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene ◽  
Ceramide Synthase ◽  
Invasion And Metastasis ◽  
Human Cancers

Abstract Homo sapiens ceramide synthase 2 (CerS-2) plays an important role in inhibiting invasion and metastasis of tumor cells and has been reported as a tumor metastasis suppressor gene in diverse cancers. Thus, low level of CerS-2 protein might suggest a bad prognosis and up-regulation of CerS-2 protein might act as a promising therapeutic strategy for malignant tumors. In this review, we discussed the expression, as well as the clinical and pathological significance of CerS-2 in diverse human cancers. The pathological processes and molecular pathways regulated by CerS-2 were also summarized.

Mutation and expression of the metastasis suppressor gene KAI1 in esophageal squamous cell carcinoma

Cancer ◽  
2000 ◽  
Vol 89 (5) ◽  
pp. 955-962 ◽  
Author(s):  
Tatsuya Miyazaki ◽  
Hiroyuki Kato ◽  
Yoshinori Shitara ◽  
Minako Yoshikawa ◽  
Kouhei Tajima ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene

Suppression of Human Melanoma Metastasis by the Metastasis Suppressor Gene, BRMS1

2002 ◽  
Vol 273 (2) ◽  
pp. 229-239 ◽  
Author(s):  
Lalita A Shevde ◽  
Rajeev S Samant ◽  
Steven F Goldberg ◽  
Tabo Sikaneta ◽  
Alessandro Alessandrini ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Human Melanoma ◽  
Metastasis Suppressor ◽  
Melanoma Metastasis ◽  
Metastasis Suppressor Gene

Abstract 3421: Nm23, a metastasis suppressor gene, binds the cytoskeletal linker Ezrin to regulate motility

2012 ◽  
Author(s):  
Jean-Claude A. Marshall ◽  
Joshua Collins ◽  
Ming Zhou ◽  
Timothy Veenstra ◽  
Chand Khanna ◽  
...  
Keyword(s):  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene

scholarly journals Regulation of tumor metastasis suppressor gene product, nm 23/nucleoside diphosphate kinase.

1996 ◽  
Vol 71 ◽  
pp. 75
Author(s):  
Jun Mukai ◽  
Satoshi Shiojima ◽  
Yasuhito Shimada ◽  
Hiroshi Ohashi. ◽  
Satoshi Matsushima ◽  
...  
Keyword(s):  
Gene Product ◽  
Tumor Metastasis ◽  
Nucleoside Diphosphate Kinase ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene
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