Inhibition of Snail-induced Epithelial-Mesenchymal Transition and Induction of the Tumor Metastasis Suppressor Gene Raf-1 Kinase Inhibitor Protein (RKIP) by DETANONOate

2010 ◽  
Vol 1 (3) ◽  
pp. 219-230 ◽  
Author(s):  
Stavroula Baritaki ◽  
Benjamin Bonavida
Keyword(s):  
Tumor Metastasis ◽  
Kinase Inhibitor ◽  
Epithelial Mesenchymal Transition ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene ◽  
Inhibitor Protein ◽  
Mesenchymal Transition

scholarly journals Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer

The Prostate ◽  
2006 ◽  
Vol 66 (3) ◽  
pp. 248-256 ◽  
Author(s):  
Zheng Fu ◽  
Yasuhide Kitagawa ◽  
Ronglai Shen ◽  
Rajal Shah ◽  
Rohit Mehra ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Prognostic Marker ◽  
Kinase Inhibitor ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene ◽  
Inhibitor Protein ◽  
Raf Kinase ◽  
Raf Kinase Inhibitor Protein

scholarly journals Clinical and pathological significance of Homo sapiens ceramide synthase 2 (CerS-2) in diverse human cancers

2019 ◽  
Vol 39 (5) ◽  
Author(s):  
Qian Zhang ◽  
Jin-yan Wang ◽  
Wei Yan ◽  
Dan-dan Wang ◽  
Su-jin Yang ◽  
...  
Keyword(s):  
Tumor Metastasis ◽  
Therapeutic Strategy ◽  
Malignant Tumors ◽  
Homo Sapiens ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene ◽  
Ceramide Synthase ◽  
Invasion And Metastasis ◽  
Human Cancers

Abstract Homo sapiens ceramide synthase 2 (CerS-2) plays an important role in inhibiting invasion and metastasis of tumor cells and has been reported as a tumor metastasis suppressor gene in diverse cancers. Thus, low level of CerS-2 protein might suggest a bad prognosis and up-regulation of CerS-2 protein might act as a promising therapeutic strategy for malignant tumors. In this review, we discussed the expression, as well as the clinical and pathological significance of CerS-2 in diverse human cancers. The pathological processes and molecular pathways regulated by CerS-2 were also summarized.

scholarly journals Regulation of tumor metastasis suppressor gene product, nm 23/nucleoside diphosphate kinase.

1996 ◽  
Vol 71 ◽  
pp. 75
Author(s):  
Jun Mukai ◽  
Satoshi Shiojima ◽  
Yasuhito Shimada ◽  
Hiroshi Ohashi. ◽  
Satoshi Matsushima ◽  
...  
Keyword(s):  
Gene Product ◽  
Tumor Metastasis ◽  
Nucleoside Diphosphate Kinase ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene

Expression and prognostic significance of a new tumor metastasis suppressor gene LASS2 in human bladder carcinoma

2011 ◽  
Vol 29 (3) ◽  
pp. 1921-1927 ◽  
Author(s):  
Haifeng Wang ◽  
Jiansong Wang ◽  
Yigang Zuo ◽  
Mingxia Ding ◽  
Ruping Yan ◽  
...  
Keyword(s):  
Bladder Carcinoma ◽  
Tumor Metastasis ◽  
Prognostic Significance ◽  
Suppressor Gene ◽  
Metastasis Suppressor ◽  
Metastasis Suppressor Gene ◽  
Human Bladder
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