Compound-Specific Risk Assessments for Genotoxic Impurities: Examples and Issues

2011 ◽  
pp. 121-149
Author(s):  
Andrew Teasdale ◽  
Charles Humfrey
Geografie ◽  
2013 ◽  
Vol 118 (3) ◽  
pp. 205-220 ◽  
Author(s):  
Jan Blahůt ◽  
Jan Klimeš ◽  
Zuzana Vařilová

Quantitative rockfall hazard and specific risk assessment of the selected municipalities within the České Švýcarsko National Park was performed using two rockfall hazard analysis modelling codes. CONEFALL and RockFall Analyst codes were used to delimit rockfall hazard regions. Specific risk to buildings was consequently assessed using results from the hazard analysis and literature-derived vulnerability values. Results of hazard and risk assessments for two nearby municipalities were compared and evaluated. Both models provide similar rockfall hazard values in areas characterized with relatively steep (36°–50°), convex and short slopes (up to 200 m). Whereas in regions with less steep (20°–35°), concave and longer slopes (about 350 m) the predicted rockfall hazard differs considerably. We argue that the results of the RockFall Analyst are more reliable due to complex input data and modelling approach which closely resembles the natural process of falling rocks on forested slopes. Differences in hazard assessment are further reflected in assigning risk values to exposed buildings, where CONEFALL is more conservative.


Author(s):  
Jean Goyet ◽  
Antoine Rouhan ◽  
Michael Havbro Faber

This paper is the first part of a report dealing with industrial implementation of Risk Based Inspection planning methods to offshore facilities. The first part deals with FPSO/FSO while the second deals with fixed steel offshore structures. The objective of the report is to convey “lessons learned” from experience using RBI methods. Theses methods aim at establishing inspection planning based on optimization procedures derived from specific risk assessments. Experience of the three authors is based on the last methodological developments in the area of RBI planning for structural components subject to fatigue degradation and on application of these methods to various types of offshore facilities. The main steps of the RBI methodology are summarized in the first paper. General conclusions related to the two types of facilities are given at the end of the second paper.


2000 ◽  
Vol 19 (2) ◽  
pp. 119-131 ◽  
Author(s):  
William F. Messier ◽  
Lizabeth A. Austen

This paper reports on a study that examines the effect of pervasive and specific risk factors on auditors' inherent risk and control risk assessments in an experimental setting. Two hypotheses concerning the significance of inherent and control risk factors on auditors' inherent risk (IR) and control risk (CR) assessments were tested by having 124 senior auditors and managers provide risk assessments on eight cases. The results show that the pervasive and specific risk factors included in the experiment were significant to both the auditors' IR and CR assessments. For the case used in this study, there was a significant positive association between auditors' IR and CR assessments. Taken together, these findings are consistent with Waller's (1993) notion of a knowledge-based dependency between IR and CR assessments. The findings are not consistent with Kinney's (1989) reformulation of the (IR×CR) component of the audit risk model.


Author(s):  
Fabian Stephany ◽  
Niklas Stoehr ◽  
Philipp Darius ◽  
Leonie Neuhäuser ◽  
Ole Teutloff ◽  
...  

2005 ◽  
Vol 173 (4S) ◽  
pp. 258-258 ◽  
Author(s):  
Shilajit D. Kundu ◽  
Kimberly A. Roehl ◽  
Jo Ann V. Antenor ◽  
William J. Catalona ◽  
Robert B. Nadler

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