scholarly journals Computed tomography–based radiomic analysis for prediction of treatment response to salvage chemoradiotherapy for locoregional lymph node recurrence after curative esophagectomy

2021 ◽  
Author(s):  
Liang Gu ◽  
Yangchen Liu ◽  
Xinwei Guo ◽  
Ye Tian ◽  
Hongxun Ye ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lymph Node ◽  
Treatment Response ◽  
Lymph Node Recurrence ◽  
Locoregional Lymph Node ◽  
Curative Esophagectomy

Toxicity and efficacy of salvage carbon 11-choline positron emission tomography/computed tomography-guided radiation therapy in patients with lymph node recurrence of prostate cancer

2016 ◽  
Vol 119 (3) ◽  
pp. 406-413 ◽  
Author(s):  
Andrei Fodor ◽  
Genoveffa Berardi ◽  
Claudio Fiorino ◽  
Maria Picchio ◽  
Elena Busnardo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Radiation Therapy ◽  
Lymph Node ◽  
Emission Tomography ◽  
Lymph Node Recurrence ◽  
Positron Emission

scholarly journals CT-based Radiomic Analysis for Prediction of Treatment Response of Salvage Chemoradiotherapy for Loco-regional Lymph Node Recurrence After Curative Esophagectomy

2021 ◽  
Author(s):  
Liang Gu ◽  
Xinwei Guo ◽  
Hongxue Ye ◽  
Shaobin Zhou ◽  
Yangchen Liu ◽  
...  
Keyword(s):  
Lymph Node ◽  
Local Recurrence ◽  
Treatment Response ◽  
Local Control ◽  
Therapeutic Response ◽  
Recurrence Time ◽  
Training Cohort ◽  
Cox Regression Analysis ◽  
Significant Difference ◽  
Curative Esophagectomy

Abstract Objective: To investigate the capability of computed tomography (CT) radiomic features to predict the therapeutic response and local control of the loco-regional recurrence lymph node (LN) after curative esophagectomy by chemoradiotherapy (CRT).Methods: This retrospective study included 129 LN from 77 patients (training cohort: 102 LN from 59 patients; validation cohort: 27 LN from 18 patients) with postoperative esophageal squamous cell carcinoma (ESCC). The region of the tumor was contoured in pretreatment contrast-enhanced CT images. The least absolute shrinkage and selection operator (LASSO) with logistic regression was used to identify radiomic predictors in the training cohort. Model performance was evaluated using the area under the receiver operating characteristic curves (AUC). The Kaplan-Meier method was used to determine the local recurrence time of cancer.Results: Seven features were selected to construct a radiomics model for predicting therapeutic response. The AUCs in the training and validated cohorts were 0.777 (95%CI: 0.667–0.878) and 0.765(95%CI: 0.556–0.975), respectively. A significant difference of radiomic score (Rad-score) between the response and non-response was observed in the two cohorts (P < 0.001, 0.034, respectively). Two features were identified for classifying whether to relapse in two years. AUC was 0.857(95%CI: 0.780–0.935) in the training cohort. The local control time of the high Rad-score group was higher than the low group in both cohorts (P < 0.001 and 0.025, respectively). After the Cox regression analysis, the Rad-score indicated high-risk factors for local recurrence within two years.Conclusions: The radiomics approach can be used as a potential imaging biomarker to predict treatment response and local control of recurrence LN in ESCC patients.

scholarly journals Loco-regional therapy for isolated locoregional lymph node recurrence of breast cancer: focusing on surgical treatment with combined therapy

2020 ◽  
Vol 9 (8) ◽  
pp. 5038-5043
Author(s):  
Kaori Terata ◽  
Ayuko Yamaguchi ◽  
Ayano Ibonai ◽  
Kazuhiro Imai ◽  
Akiyuki Wakita ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Surgical Treatment ◽  
Combined Therapy ◽  
Regional Therapy ◽  
Lymph Node Recurrence ◽  
Locoregional Lymph Node

scholarly journals Efficacy and Safety of Chemoradiotherapy for Patients with Locoregional Lymph Node Recurrence of Esophageal Squamous Cell Carcinoma

2012 ◽  
Vol 23 ◽  
pp. xi138
Author(s):  
T. Funakoshi ◽  
T. Tsushima ◽  
Y. Shibata ◽  
H. Tabuse ◽  
H. Sawai ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Efficacy And Safety ◽  
Lymph Node Recurrence ◽  
Locoregional Lymph Node

scholarly journals Locoregional Lymph Node Recurrence of Trunk Melanoma in Non-sentinel Lymph Node Basins: An Observational Retrospective Study

2020 ◽  
pp. 0 ◽  
Author(s):  
R Moro ◽  
J González-Ramos ◽  
S Martínez-García ◽  
C Requena ◽  
V Traves ◽  
...  
Keyword(s):  
Lymph Node ◽  
Retrospective Study ◽  
Sentinel Lymph Node ◽  
Lymph Node Recurrence ◽  
Locoregional Lymph Node
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