scholarly journals Does C-Reactive Protein Predict the Long-Term Progression of Interstitial Lung Disease and Survival in Patients With Early Systemic Sclerosis?

2013 ◽  
Vol 65 (8) ◽  
pp. 1375-1380 ◽  
Author(s):  
Xiaochun Liu ◽  
Maureen D. Mayes ◽  
Claudia Pedroza ◽  
Hilda T. Draeger ◽  
Emilio B. Gonzalez ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Early Systemic Sclerosis

scholarly journals CCL2 in the Circulation Predicts Long-Term Progression of Interstitial Lung Disease in Patients With Early Systemic Sclerosis: Data From Two Independent Cohorts

2017 ◽  
Vol 69 (9) ◽  
pp. 1871-1878 ◽  
Author(s):  
Minghua Wu ◽  
Murray Baron ◽  
Claudia Pedroza ◽  
Gloria A. Salazar ◽  
Jun Ying ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Early Systemic Sclerosis

Tocilizumab Prevents Progression of Early Systemic Sclerosis Associated Interstitial Lung Disease

2021 ◽  
Author(s):  
David Roofeh ◽  
Celia J F Lin ◽  
Jonathan Goldin ◽  
Grace Hyun Kim ◽  
Daniel E Furst ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Early Systemic Sclerosis

Incidence and predictors of interstitial lung disease (ILD) in Thai patients with early systemic sclerosis: Inception cohort study

2015 ◽  
Vol 26 (4) ◽  
pp. 588-593 ◽  
Author(s):  
Suparaporn Wangkaew ◽  
Juntima Euathrongchit ◽  
Pittaporn Wattanawittawas ◽  
Nuntana Kasitanon ◽  
Worawit Louthrenoo
Keyword(s):  
Cohort Study ◽  
Systemic Sclerosis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Inception Cohort ◽  
Early Systemic Sclerosis

scholarly journals Anti-HLA Class II Antibodies Correlate with C-Reactive Protein Levels in Patients with Rheumatoid Arthritis Associated with Interstitial Lung Disease

Cells ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 691
Author(s):  
Alma D. Del Angel-Pablo ◽  
Ivette Buendía-Roldán ◽  
Mayra Mejía ◽  
Gloria Pérez-Rubio ◽  
Karol J. Nava-Quiroz ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Class Ii ◽  
Hla Class Ii ◽  
C Reactive Protein ◽  
Hla Antibodies ◽  
Protein Levels ◽  
Reactive Protein ◽  
Genetic And Environmental Factors

The pathogenesis of Rheumatoid Arthritis (RA) is not fully understood, probably influenced by genetic and environmental factors. Interstitial Lung Disease (ILD) is an extra-articular manifestation of RA, which contributes significantly to morbidity and mortality. The identification of anti-HLA antibodies has been useful in the transplantation field; however, its contribution to autoimmune diseases as RA has not been fully studied. We aimed to determine the presence of anti-HLA antibodies in RA patients with and without ILD and its possible association with clinical and biochemical markers. One-hundred and forty-seven RA patients, of which 65 had ILD (RA-ILD group), were included. Sera samples for Anti-HLA Class II LABScreen panel-reactive antibodies (PRA) were analyzed. In both groups, women predominated, and lung function was worse in patients with ILD. The anti-CCP+ (UI/mL) was higher in the RA group in comparison to RA-ILD (p < 0.001). Expositional risk factors (tobacco smoking and biomass-burning smoke) were higher in RA-ILD patients. PRA+ was identified in ~25% RA-ILD patients, while ~29% in the RA group. The CRP levels have a positive correlation with the percentage of reactivity (%PRA, p = 0.02, r2 = 0.60) in the RA-ILD group. In conclusion, anti-HLA antibodies correlate with C-reactive protein levels in RA patients with ILD.

scholarly journals Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort

2010 ◽  
Vol 12 (5) ◽  
pp. R166 ◽  
Author(s):  
Shervin Assassi ◽  
Roozbeh Sharif ◽  
Robert E Lasky ◽  
Terry A McNearney ◽  
Rosa M Estrada-Y-Martin ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Systemic Sclerosis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Prospective Longitudinal Study ◽  
Prospective Longitudinal ◽  
Early Systemic Sclerosis
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