Recent Advances for Improving Functionality, Biocompatibility, and Longevity of Implantable Medical Devices and Deliverable Drug Delivery Systems

2021 ◽  
pp. 2010929
Author(s):  
Neta Kutner ◽  
Konda Reddy Kunduru ◽  
Luna Rizik ◽  
Shady Farah
2020 ◽  
Vol 6 (3) ◽  
pp. 85-86
Author(s):  
Niels Grabow ◽  
Volkmar Senz ◽  
Klaus-Peter Schmitz

AbstractThe consortium RESPONSE is a cooperation of partners from science and industry within the BMBFProgram “Twenty20 - Partnership for Innovation”, 2014- 2021. Current efforts are being made towards the transfer of new products, technologies and processes in the field of medical devices. Here, RESPONSE is focusing on novel concepts of implantable medical devices for cardiovascular, ophthalmologic and otolaryngologic application. Platform technology approaches, such as drug delivery systems for responsive functionalized implants or smart implant technologies, are being used to enable new applications.


2013 ◽  
Vol 40 (10) ◽  
pp. 1014
Author(s):  
Xiao-Hong HAO ◽  
Cui-Miao ZHANG ◽  
Xiao-Long LIU ◽  
Xing-Jie LIANG ◽  
Guang JIA ◽  
...  

2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.


2011 ◽  
Vol 1 (2) ◽  
pp. 135-149
Author(s):  
Jose Maria Bermudez ◽  
Daniela Quinteros ◽  
Ricardo Grau ◽  
Daniel Allemandi ◽  
Santiago Palma

Nanomedicine ◽  
2021 ◽  
Author(s):  
Ahmed S AbdElhamid ◽  
Dina G Zayed ◽  
Lamia Heikal ◽  
Sherine N Khattab ◽  
Omar Y Mady ◽  
...  

Polymeric nanocapsules are vesicular drug delivery systems composed of an inner oily reservoir surrounded by polymeric membranes. Nanocapsules have various advantages over other nanovesicular systems such as providing controlled drug release properties. We discuss the recent advances in polymeric shell-oily core nanocapsules, illustrating the different types of polymers used and their implementation. Nanocapsules can be utilized for many purposes, especially encapsulation of highly lipophilic drugs. They have been shown to have variable applications, especially in cancer therapy, due to the ability of the polymeric shell to direct the loaded drugs to their target sites, as well as their high internalization efficacy. Those productive applications guaranteed their high potential as drug delivery systems. However, their clinical development is still in an early stage.


2011 ◽  
Vol 02 (05) ◽  
pp. 510-526 ◽  
Author(s):  
Nuno Martinho ◽  
Christiane Damgé ◽  
Catarina Pinto Reis

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