scholarly journals Transfer activities for cardiovascular, ophthalmologic and otolaryngologic medical device innovations

2020 ◽  
Vol 6 (3) ◽  
pp. 85-86
Author(s):  
Niels Grabow ◽  
Volkmar Senz ◽  
Klaus-Peter Schmitz
Keyword(s):  
Drug Delivery ◽  
Medical Device ◽  
Medical Devices ◽  
Drug Delivery Systems ◽  
New Products ◽  
Delivery Systems ◽  
Implantable Medical Devices ◽  
Platform Technology ◽  
New Applications

AbstractThe consortium RESPONSE is a cooperation of partners from science and industry within the BMBFProgram “Twenty20 - Partnership for Innovation”, 2014- 2021. Current efforts are being made towards the transfer of new products, technologies and processes in the field of medical devices. Here, RESPONSE is focusing on novel concepts of implantable medical devices for cardiovascular, ophthalmologic and otolaryngologic application. Platform technology approaches, such as drug delivery systems for responsive functionalized implants or smart implant technologies, are being used to enable new applications.

scholarly journals Perivascular medical devices and drug delivery systems: Making the right choices

Biomaterials ◽  
2017 ◽  
Vol 128 ◽  
pp. 56-68 ◽  
Author(s):  
Ioanna Mylonaki ◽  
Éric Allémann ◽  
François Saucy ◽  
Jacques-Antoine Haefliger ◽  
Florence Delie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Medical Devices ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
The Right

scholarly journals Medical device innovations for cardiovascular, ophthalmologic and otolaryngologic applications

2019 ◽  
Vol 5 (1) ◽  
pp. 117-118
Author(s):  
Niels Grabow ◽  
Volkmar Senz ◽  
Klaus-Peter Schmitz
Keyword(s):  
Medical Device ◽  
Medical Devices ◽  
Implantable Medical Devices ◽  
Platform Technology ◽  
Device Applications ◽  
Innovation Processes

AbstractThe consortium RESPONSE is a cooperation between partners from science and industry within the BMBF-Program “Twenty20 - Partnership for Innovation”, 2014-2021. RESPONSE gives its partners opportunities to put medical device innovations into practice more efficiently. In order to accelerate innovation processes, joint efforts are being made along the entire translation chain. RESPONSE is focusing on the development of novel concepts of implantable medical devices for cardiovascular, ophthalmologic and ENT application. Platform technology approaches are being used to extend the range of device applications. See also: www.response.uni-rostock.de

Smart drug delivery systems: from fundamentals to the clinic

2014 ◽  
Vol 50 (58) ◽  
pp. 7743-7765 ◽  
Author(s):  
Carmen Alvarez-Lorenzo ◽  
Angel Concheiro
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Medical Devices ◽  
Smart Materials ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Smart Drug ◽  
Smart Drug Delivery

Smart materials can endow implantable depots, targetable nanocarriers and insertable medical devices with activation-modulated and feedback-regulated control of drug release.

Recent Advances in Gastro-Retentive Drug Delivery Systems

2016 ◽  
Vol 9 (3) ◽  
pp. 3221-3254
Author(s):  
Korlapati Venkateswara Rao ◽  
V.V. Venkatachalam
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Recent Literature ◽  
New Products ◽  
Delivery Systems ◽  
Local Drug Delivery ◽  
Special Focus ◽  
Therapeutic Activity ◽  
Proximal Small Intestine ◽  
Absorption Window

Controlled  gastric  retention  of  solid  dosage  form  may  be  achieved  by  the  mechanisms  of  floatation,  muco-adhesion,  sedimentation,  expansion  or  by  a  modified  shaped  system. The purpose of this paper is to review the recent literature and current technology used in the development of gastroretentive drug delivery systems. Oral sustained release gastroretentive dosage forms offer many advantages for drugs having absorption from upper gastrointestinal tract and improve the bioavailability of medications that are characterized by a narrow absorption window. Gastroretention would also facilitate local drug delivery to the stomach and proximal small intestine. So, gastroretention could help to provide greater availability of new products and consequently improved therapeutic activity and required benefits to patients. The purpose of writing the article was to compile the recent literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. In particular, bioadhesive, size-increasing and floating drug delivery systems are presented and their major advantages and shortcomings are critically discussed in this review. Thus, gastroretention could help to provide greater availability of new products  and  consequently  improved  therapeutic  activity  and  substantial  benefits  to  patients

scholarly journals Applications of Biopolymers for Drugs and Probiotics Delivery

Polymers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2729
Author(s):  
Roxana Gheorghita ◽  
Liliana Anchidin-Norocel ◽  
Roxana Filip ◽  
Mihai Dimian ◽  
Mihai Covasa
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Medical Community ◽  
Practical Applications ◽  
Food Applications ◽  
Product Delivery ◽  
Pharmaceutical Industries ◽  
Support Of Research ◽  
New Applications

Research regarding the use of biopolymers has been of great interest to scientists, the medical community, and the industry especially in recent years. Initially used for food applications, the special properties extended their use to the pharmaceutical and medical industries. The practical applications of natural drug encapsulation materials have emerged as a result of the benefits of the use of biopolymers as edible coatings and films in the food industry. This review highlights the use of polysaccharides in the pharmaceutical industries and as encapsulation materials for controlled drug delivery systems including probiotics, focusing on their development, various applications, and benefits. The paper provides evidence in support of research studying the use of biopolymers in the development of new drug delivery systems, explores the challenges and limitations in integrating polymer-derived materials with product delivery optimization, and examines the host biological/metabolic parameters that can be used in the development of new applications.

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

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