An increasing number of attention is being paid to perovskite oxides due to their relatively low prices and comparable ability in being an alternative choice to replace high-priced metal catalyst in many fields. In this work, a group of Ti/Nb co-doped SrCoO3-δ-based perovskite oxides SrTixNb0.2-xCo0.8O3-δ (x=0, 0.05, 0.1, 0.15, 0.175, 0.2) were synthesized and measured as candidates for oxygen evolution reaction (OER). Among all the perovskite samples, SrTixNb0.2-xCo0.8O3-δ (x=0.175, STNC-4) displayed the lowest OER overpotential of 0.4 V and the lowest Tafel plots as well as fastest charge transfer ability. This catalyst also revealed a great durability in alkaline solution.