scholarly journals Growing Trans‐Species Islets in Tumor Extract‐Remodeled Testicles

2019 ◽  
Vol 6 (6) ◽  
pp. 1801694
Author(s):  
Zhenzhen Wang ◽  
Xiaying Rui ◽  
Junni Qiu ◽  
Yiqing Yan ◽  
Jingjing Gan ◽  
...  
Keyword(s):  
Tumor Extract

scholarly journals Islet Transplantation: Growing Trans‐Species Islets in Tumor Extract‐Remodeled Testicles (Adv. Sci. 6/2019)

2019 ◽  
Vol 6 (6) ◽  
pp. 1970036 ◽  
Author(s):  
Zhenzhen Wang ◽  
Xiaying Rui ◽  
Junni Qiu ◽  
Yiqing Yan ◽  
Jingjing Gan ◽  
...  
Keyword(s):  
Islet Transplantation ◽  
Tumor Extract

Abstract 2172: Quantification of ERK activity in cancer cell lysates and tumor extract using differential sensing methods

2019 ◽  
Author(s):  
Diana Zamora-Olivares ◽  
Tamer S. Kaoud ◽  
Lingyu Zeng ◽  
Mitchell Telles ◽  
Eric V. Anslyn ◽  
...  
Keyword(s):  
Cancer Cell ◽  
Cell Lysates ◽  
Tumor Extract ◽  
Erk Activity

scholarly journals THE CONSTITUTION OF MITOCHONDRIA AND MICROSOMES, AND THE DISTRIBUTION OF NUCLEIC ACID IN THE CYTOPLASM OF A LEUKEMIC CELL

1944 ◽  
Vol 80 (1) ◽  
pp. 19-29 ◽  
Author(s):  
Albert Claude
Keyword(s):  
Nucleic Acid ◽  
Phosphorus Content ◽  
Leukemic Cell ◽  
Leukemic Cells ◽  
Low Molecular Weight ◽  
Elementary Composition ◽  
The Third ◽  
Large Size ◽  
Tumor Extract ◽  
Rat Tumor

1. Rat tumor extracts, containing chiefly the cytoplasmic constituents of leukemic cells, were fractionated into three main portions, the different components separating in the centrifuge according to size. 2. Mitochondria were isolated by centrifugation at relatively low speed. Elementary composition of purified mitochondria was found to correspond to about 11.5 per cent nitrogen, 1.6 per cent phosphorus, and 27 per cent lipids. Phosphorus and nitrogen content of the lipid portion suggests that as much as 75 to 80 per cent of the lipids of mitochondria is represented by phospholipids. Tests for ribose nucleic acid were positive. 3. Microsomes were separated by means of centrifugation at 18,000 x g. A relation between the high phosphorus content of the microsomes and the marked basophilia of the cytoplasm of leukemic cells is suggested. 4. Phosphorus distribution in the tumor extract, and light absorption analysis of the third fraction, seem to demonstrate that nucleic acid was not present either in a free condition, or in the form of nucleoprotein of relatively low molecular weight. The nature of the results suggests that ribose nucleic acid occurs in the cytoplasm of leukemic cells only in association with formed elements of relatively large size, namely microsomes, and mitochondria.

Effect of Operation on Cell-Mediated Immune Response to Autologous Tumor Extract in Cancer Patients

1983 ◽  
Vol 130 (2) ◽  
pp. 403-403
Author(s):  
S. Miyazaki ◽  
T. Akiyoshi ◽  
M. Kawaguchi ◽  
F. Koba ◽  
S. Arinaga ◽  
...  
Keyword(s):  
Immune Response ◽  
Cancer Patients ◽  
Autologous Tumor ◽  
Cell Mediated Immune Response ◽  
Tumor Extract

Enhancement of Th1 immune response by CD8α+ dendritic cells loaded with heat shock proteins enriched tumor extract in tumor-bearing mice

2009 ◽  
Vol 260 (1) ◽  
pp. 28-32 ◽  
Author(s):  
Abbas Azadmehr ◽  
Ali Akbar Pourfathollah ◽  
Zahra Amirghofran ◽  
Zuhair Mohammad Hassan ◽  
Seyed Mohammad Moazzeni
Keyword(s):  
Immune Response ◽  
Dendritic Cells ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Tumor Bearing ◽  
Tumor Extract ◽  
Shock Proteins ◽  
Th1 Immune Response

Dendritic cells transfected with interleukin-12 and pulsed with tumor extract inhibit growth of murine prostatic carcinoma in vivo

The Prostate ◽  
2003 ◽  
Vol 55 (4) ◽  
pp. 292-298 ◽  
Author(s):  
Shaobo Zhang ◽  
Guangyuan Zeng ◽  
David S. Wilkes ◽  
Gerry E. Reed ◽  
Ronald C. McGarry ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Prostatic Carcinoma ◽  
Interleukin 12 ◽  
Tumor Extract

Transplantation antigens in tumors, tumor extract and cell-free ascitic fluid

1962 ◽  
Vol 30 (1) ◽  
pp. 200
Author(s):  
V Hašková ◽  
I Hilgert
Keyword(s):  
Ascitic Fluid ◽  
Tumor Extract ◽  
Transplantation Antigens

scholarly journals RGD Collagen for Engineering a Contractile Tissue and Cell Therapy after Myocardial Infarct

2021 ◽  
Author(s):  
Olivier schussler ◽  
pierre-emmanuel falcoz ◽  
Juan-Carlos Chachques ◽  
Marco Alifano ◽  
Yves lecarpentier
Keyword(s):  
Cell Therapy ◽  
Heart Development ◽  
Myocardial Infarct ◽  
Clinical Impact ◽  
Cardiac Cells ◽  
3D Scaffold ◽  
Secondary Migration ◽  
Cell Engraftment ◽  
Tumor Extract ◽  
Contractile Tissue

Currently, the clinical impact of cell therapy after a myocardial infarction (MI) is limited by low cell engraftment due to significant cell death, including apoptosis, in an infarcted, inflammatory, poor angiogenic environment, low cell retention and secondary migration. Cells interact with their environment through integrin mechanoreceptors that control their survival/apoptosis/differentiation/migration/proliferation. Optimizing these interactions may be a way of improving outcomes. The association of free cells with a 3D-scaffold may be a way to target their integrins. Collagen is the most abundant structural component of the extracellular matrix (ECM) and the best contractility levels are achieved with cellular preparations containing collagen, fibrin, or Matrigel (i.e. tumor extract). In the interactions between cells and ECM, 3 main proteins are recognised: collagen, laminin and RGD (Arg-Gly-Asp) peptide. The RGD plays a key role in heart development, after MI, and on cardiac cells. Cardiomyocytes secrete their own laminin on collagen. The collagen has a non-functional cryptic RGD and is thus suboptimal for interactions with associated cells. The use of a collagen functionalized with RGD may help to improve collagen biofunctionality. It may help in the delivery of paracrine cells, whether or not they are contractile, and in assisting tissue engineering a safe contractile tissue.

Comparative study of the immunologic response to injection of tumor extract into newborn and adult animals

1975 ◽  
Vol 79 (6) ◽  
pp. 683-685
Author(s):  
M. F. Nikonova ◽  
I. N. Maiskii ◽  
T. A. Pokrovskaya
Keyword(s):  
Comparative Study ◽  
Immunologic Response ◽  
Tumor Extract

Inhibition of Leukocyte Migration by a Human Colon Cancer Extract

1981 ◽  
Vol 67 (3) ◽  
pp. 163-167 ◽  
Author(s):  
Maria Caterina Sirianni ◽  
Giuseppe Luzi ◽  
Claudio Iavarone ◽  
Marisa Papaluca ◽  
Massimo Fiorilli ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Human Colon ◽  
Control Group ◽  
Migration Inhibition ◽  
Human Colon Cancer ◽  
Tumor Associated Antigen ◽  
Leucocyte Migration ◽  
Tumor Extract ◽  
Leucocyte Migration Inhibition Test ◽  
Leucocyte Migration Inhibition

The direct leucocyte migration inhibition test in capillary tubes was used to test 10 patients with colonic adenocarcinoma against KCl soluble extracts of an allogenic colon cancer and an allogenic normal colon fragment. Inhibition was consistently found with the cancer extract but not with the normal tissue extract. None of the control group of patients affected by other tumors, intestinal and liver disorders showed a migration inhibition in response to the colonic tumor extract. Our findings strongly suggest the presence of a tumor-associated antigen in the cancer extract.

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