scholarly journals Association of cardiovascular risk burden with risk of dementia and brain pathologies: A population‐based cohort study

2021 ◽  
Author(s):  
Ruixue Song ◽  
Kuan‐Yu Pan ◽  
Hui Xu ◽  
Xiuying Qi ◽  
Aron S. Buchman ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Risk ◽  
Population Based

scholarly journals Gender Inequalities in Diagnostic Inertia around the Three Most Prevalent Cardiovascular Risk Studies: Protocol for a Population-Based Cohort Study

2021 ◽  
Vol 18 (8) ◽  
pp. 4054
Author(s):  
Concepción Carratala-Munuera ◽  
Adriana Lopez-Pineda ◽  
Domingo Orozco-Beltran ◽  
Jose A. Quesada ◽  
Jose L. Alfonso-Sanchez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Health Care ◽  
Cohort Study ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Disease Incidence ◽  
Population Based ◽  
Gender Inequalities ◽  
Primary Health Care Centers

Evidence shows that objectives for detecting and controlling cardiovascular risk factors are not being effectively met, and moreover, outcomes differ between men and women. This study will assess the gender-related differences in diagnostic inertia around the three most prevalent cardiovascular risk factors: dyslipidemia, arterial hypertension, and diabetes mellitus, and to evaluate the consequences on cardiovascular disease incidence. This is an epidemiological and cohort study. Eligible patients will be adults who presented to public primary health care centers in a Spanish region from 2008 to 2011, with hypertension, dyslipidemia, or/and diabetes and without cardiovascular disease. Participants’ electronic health records will be used to collect the study variables in a window of six months from inclusion. Diagnostic inertia of hypertension, dyslipidemia, and/or diabetes is defined as the registry of abnormal diagnostic parameters—but no diagnosis—on the person’s health record. The cohort will be followed from the date of inclusion until the end of 2019. Outcomes will be cardiovascular events, defined as hospital admission due to ischemic cardiopathy, stroke, and death from any cause. The results of this study could inform actions to rectify the structure, organization and training of health care teams in order to correct the inequality.

scholarly journals Prepregnancy Cardiovascular Risk Factors as Predictors of Preeclampsia: Population-based Cohort Study

2008 ◽  
Vol 28 (2) ◽  
pp. 79 ◽  
Author(s):  
E.B. Magnussen ◽  
L.J. Vatten ◽  
T.I. Lund-Nilsen ◽  
K.A. Salvesen ◽  
G. Davey Smith ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Population Based

scholarly journals Effectiveness of Statins as Primary Prevention in People With Different Cardiovascular Risk: A Population-Based Cohort Study

2018 ◽  
Vol 104 (4) ◽  
pp. 719-732 ◽  
Author(s):  
Maria Garcia-Gil ◽  
Marc Comas-Cufí ◽  
Jordi Blanch ◽  
Ruth Martí ◽  
Anna Ponjoan ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Risk ◽  
Primary Prevention ◽  
Population Based

scholarly journals Cerebral small vessel disease, cardiovascular risk factors, and future walking speed in old age: a population-based cohort study

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Emerald G. Heiland ◽  
Anna-Karin Welmer ◽  
Grégoria Kalpouzos ◽  
Anna Laveskog ◽  
Rui Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Cardiovascular Risk ◽  
Cognitive Function ◽  
Walking Speed ◽  
Small Vessel Disease ◽  
Population Based ◽  
Cerebral Small Vessel Disease ◽  
Vessel Disease

Abstract Background The purpose of this study was to examine the associations between combined and individual cerebral small vessel disease (cSVD) markers on future walking speed over 9 years; and to explore whether these associations varied by the presence of cardiovascular risk factors (CRFs). Methods This population-based cohort study included 331 adults, aged ≥60 years, without limitation in walking speed (≥0.8 m/s). At baseline, cSVD markers, including white matter hyperintensities (WMH), lacunes, and perivascular spaces (PVS), were assessed on magnetic resonance imaging. The modifiable CRFs (physical inactivity, heavy alcohol consumption, smoking, hypertension, high total cholesterol, diabetes, and overweight/obese) were combined into a score. The association between baseline cSVD markers and the decline in walking speed was examined using linear mixed-effects models, whereas Cox proportional hazards models were used to estimate the association with walking speed limitation (defined as < 0.8 m/s) over the follow-up. Results Over the follow-up period, 76 (23.0%) persons developed walking speed limitation. Participants in the highest tertile of the combined cSVD marker score had a hazard ratio (HR) of 3.78 (95% confidence interval [CI] 1.70-8.45) for walking speed limitation compared with people in the lowest score tertile, even after adjusting for socio-demographics, CRFs, cognitive function, and chronic conditions. When investigating the cSVD markers individually, having the highest burden of WMH was associated with a significantly faster decline in walking speed (β coefficient − 0.020; 95% CI -0.035-0.004) and a greater HR of walking speed limitation (HR 2.78; 95% CI 1.31-5.89) compared with having the lowest WMH burden. Similar results were obtained for the highest tertile of PVS (HR 2.13; 95% CI 1.04-4.36). Lacunes were associated with walking speed limitation, but only in men. Having ≥4 CRFs and high WMH volume simultaneously, showed a greater risk of walking speed limitation compared with having ≥4 CRFs and low WMH burden. CRFs did not modify the associations between lacunes or PVS and walking speed. Conclusions Combined cSVD markers strongly predict walking speed limitation in healthy older adults, independent of cognitive function, with WMH and PVS being the strongest contributors. Improving cardiovascular health may help to mitigate the negative effects of WMH on future walking speed.

Early cardiovascular risk and all‐cause mortality following an incident of severe hypoglycaemia: A population‐based cohort study

2019 ◽  
Vol 21 (8) ◽  
pp. 1878-1885 ◽  
Author(s):  
Shih‐Chang Lo ◽  
Yi‐Sun Yang ◽  
Edy Kornelius ◽  
Jing‐Yang Huang ◽  
Yung‐Rung Lai ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiovascular Risk ◽  
Severe Hypoglycaemia ◽  
Population Based ◽  
All Cause Mortality

scholarly journals Cardiovascular Risk is not Increased in Patients with Chronic Urticaria: A Retrospective Population-based Cohort Study

2017 ◽  
Vol 97 (2) ◽  
pp. 261-262 ◽  
Author(s):  
A Egeberg ◽  
K Kofoed ◽  
G Gislason ◽  
C Vestergaard ◽  
J Thyssen
Keyword(s):  
Cohort Study ◽  
Cardiovascular Risk ◽  
Chronic Urticaria ◽  
Population Based

scholarly journals First trimester fetal growth restriction and cardiovascular risk factors in school age children: population based cohort study

BMJ ◽  
2014 ◽  
Vol 348 (jan23 1) ◽  
pp. g14-g14 ◽  
Author(s):  
V. W. V. Jaddoe ◽  
L. L. de Jonge ◽  
A. Hofman ◽  
O. H. Franco ◽  
E. A. P. Steegers ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Fetal Growth ◽  
Fetal Growth Restriction ◽  
First Trimester ◽  
Population Based ◽  
School Age Children ◽  
School Age
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