scholarly journals Natural history of denervation in SMA: Relation to age,SMN2 copy number, and function

2005 ◽  
Vol 57 (5) ◽  
pp. 704-712 ◽  
Author(s):  
Kathryn J. Swoboda ◽  
Thomas W. Prior ◽  
Charles B. Scott ◽  
Teresa P. McNaught ◽  
Mark C. Wride ◽  
...  
Keyword(s):  
Natural History ◽  
Copy Number ◽  
History Of ◽  
And Function

scholarly journals Trapeziometacarpal joint arthritis: A retrospective study of the natural history of symptomatic thumb arthritis

2019 ◽  
Vol 5 (2) ◽  
pp. 11
Author(s):  
Jessica Frankenhoff ◽  
Jeffrey Stromberg ◽  
Aimee Riley ◽  
Jun He ◽  
Prem Madesh ◽  
...  
Keyword(s):  
Natural History ◽  
Retrospective Chart Review ◽  
Treatment Modalities ◽  
Common Source ◽  
Average Pain ◽  
Average Pain Score ◽  
History Of ◽  
And Function ◽  
Joint Arthritis

Objective: Trapeziometacarpal (TM) joint arthritis is a common source of hand pain in patients presenting to the hand surgeon’s clinic. Long-term data on the natural history of symptomatic TM arthritis is lacking.Methods: We identified 251 patients with symptomatic TM arthritis and performed a retrospective chart review which identified treatment modalities (including surgery) and long term outcomes which were assessed via a telephone survey.Results: We found that of the 251 patients who presented with symptomatic TM arthritis, the 114 patients who had surgery had less pain and disability in the long term than those patients who were treated conservatively with splinting or injection (average pain score 1.8 vs. 3.8). However, the majority of patients did not ultimately undergo surgery.Conclusions: Although patients fare better from a pain and function standpoint with surgery, surgery is not inevitable.

Diagnosis and investigation in suspected heart disease

2018 ◽  
Author(s):  
Colin Forfar
Keyword(s):  
Natural History ◽  
Scientific Evidence ◽  
Treatment Options ◽  
Case Fatality ◽  
The Past ◽  
Good Patient Care ◽  
History Of ◽  
Coronary Syndromes ◽  
Complete Physical Examination ◽  
And Function

The past 20 years have seen significant changes in both the demographics and natural history of many cardiovascular diseases. Important reductions in case-fatality rates (such as in acute coronary syndromes) have resulted from improved diagnostics and treatment options and better understanding of natural history. For others (such as infective endocarditis), improvements have been limited and disappointing. While advances in therapy and the scientific evidence underpinning treatments have been crucial, the importance of accurate diagnosis has remained a key element for progress. Many of the principles needed for diagnosis are constant: the pre-eminence of a focused, accurate history, complete physical examination, and timely and relevant investigation endures. It is essential to have a secure knowledge of the strengths and limitations of interpretation of a frequently bewildering array of tests. Progress in this field has been rapid; advances in ultrasound, scintigraphy, and cardiac magnetic resonance stand out at the interface between structure and function central to good patient care.

The natural history of endothelial structure and function in arterialized vein grafts

1986 ◽  
Vol 3 (2) ◽  
pp. 204-215 ◽  
Author(s):  
Harry L. Bush ◽  
Joseph A. Jakubowski ◽  
G. Richard Curl ◽  
Daniel Deykin ◽  
Donald C. Nabseth
Keyword(s):  
Natural History ◽  
Structure And Function ◽  
Vein Grafts ◽  
History Of ◽  
And Function

scholarly journals The natural history of endothelial structure and function in arterialized vein grafts

1986 ◽  
Vol 3 (2) ◽  
pp. 204-215 ◽  
Author(s):  
Harry L. Bush ◽  
Joseph A. Jakubowski ◽  
G.Richard Curl ◽  
Daniel Deykin ◽  
Donald C. Nabseth
Keyword(s):  
Natural History ◽  
Structure And Function ◽  
Vein Grafts ◽  
History Of ◽  
And Function

How is the moral stance related to the intentional stance and group thinking?

2020 ◽  
Vol 43 ◽  
Author(s):  
Hannes Rakoczy
Keyword(s):  
Natural History ◽  
Social Cognitive ◽  
Intentional Stance ◽  
Cognitive Capacities ◽  
Shared Intentionality ◽  
History Of ◽  
Group Thinking ◽  
Moral Stance

Abstract The natural history of our moral stance told here in this commentary reveals the close nexus of morality and basic social-cognitive capacities. Big mysteries about morality thus transform into smaller and more manageable ones. Here, I raise questions regarding the conceptual, ontogenetic, and evolutionary relations of the moral stance to the intentional and group stances and to shared intentionality.

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