pH-responsive release behavior of genipin-crosslinked chitosan/poly(ethylene glycol) hydrogels

2012 ◽  
Vol 125 (S2) ◽  
pp. E290-E298 ◽  
Author(s):  
Yangshuo Liu ◽  
Wenbao Chen ◽  
Hyung-Il Kim
Keyword(s):  
Ethylene Glycol ◽  
Release Behavior ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Crosslinked Chitosan ◽  
Poly Ethylene

A pH-responsive polymer based on dynamic imine bonds as a drug delivery material with pseudo target release behavior

2018 ◽  
Vol 9 (7) ◽  
pp. 878-884 ◽  
Author(s):  
Yangchun Tao ◽  
Siwei Liu ◽  
Yi Zhang ◽  
Zhenguo Chi ◽  
Jiarui Xu
Keyword(s):  
Drug Delivery ◽  
Schiff Base ◽  
Ethylene Glycol ◽  
Release Behavior ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Triggered Release ◽  
Responsive Polymer ◽  
Poly Ethylene

In this study, pentaerythritol tetra(3-mercaptopropionate)-allylurea-poly(ethylene glycol) (PETMP-AU-PEG), produced by the Schiff-base reaction between terminal-aldehyded PEG and PETMP-AU, was used to prepare doxorubicin (DOX)-loaded polymers for triggered release.

One-shot synthesis and solution properties of ROS/pH responsive methoxy poly(ethylene glycol)-b-polycarbonate

2019 ◽  
Vol 10 (17) ◽  
pp. 2143-2151 ◽  
Author(s):  
Yan Zhang ◽  
Yue Xu ◽  
Chao Wei ◽  
Chuanhao Sun ◽  
Bingkun Yan ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Tertiary Amine ◽  
Solution Properties ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Amine Groups ◽  
Poly Ethylene

A one-shot method was employed to synthesize ROS/pH responsive methoxy poly(ethylene glycol)-b-polycarbonate (mPEG-b-poly(MN-co-MSe)) with the selenide and tertiary amine groups situated on the backbone.

Star-shaped poly(l-lactide)-b-poly(ethylene glycol) with porphyrin core: synthesis, self-assembly, drug-release behavior and singlet oxygen research

2014 ◽  
Vol 38 (8) ◽  
pp. 3569-3578 ◽  
Author(s):  
Xiao-Hui Dai ◽  
Zhi-Ming Wang ◽  
Lu-You Gao ◽  
Jian-Ming Pan ◽  
Xiao-Hong Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Block Copolymer ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Release Behavior ◽  
Poly Ethylene Glycol ◽  
Drug Release Behavior ◽  
Porphyrin Core ◽  
Poly Ethylene

pH-induced block copolymer SPPLA-b-PEG with porphyrin core for photodynamic therapy.

A Tunable pH-Responsive Nanomaterials for Cancer Delivery

2013 ◽  
Vol 750-752 ◽  
pp. 1476-1479 ◽  
Author(s):  
Bin Liu ◽  
Guan Hui Gao ◽  
Peng Liu ◽  
Hu Qiang Yi ◽  
Wei Wei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ethylene Glycol ◽  
Potential Application ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Positive Potential ◽  
Ph Values ◽  
Drugs In Blood ◽  
Poly Ethylene

In this paper, we successfully designed a pH-responsive micelles based on hybrid polypeptide copolymers of poly (L-lysine-4-Azepan-1-yl-butyric)-b-poly (ethylene glycol)-b-poly (L-lysine-Diisopropylamide)-b-poly (L-leucine) (PLL(A)-PEG-PLL(B)-PLLeu) for efficient drug delivery. This pH-responsive nanoparticles were able to response to different pH values (pH=6.8 and 5.5). In vitro, these nanoparticles exhibited a stable and evenly distributed approximately 51 nm, a slightly positive potential about 10.3 mv at pH 7.4, which were crucial for the circulation of drugs in blood. While size and potential were about 130 nm and 34.7 mv at pH 6.8, which were good for drugs in membrane. Furthermore, the loading capability of DOX was up to 11.3%, and the pH-responsive release efficiency reached to 68.3% at pH 5.5. The results indicated that these micelles had huge potential application in cancer delivery.

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