scholarly journals Editorial: Methods for systems metabolic engineering and downstream processing

2010 ◽  
Vol 5 (6) ◽  
pp. 537-537 ◽  
Author(s):  
Uta Schaefer
Keyword(s):  
Metabolic Engineering ◽  
Downstream Processing ◽  
Systems Metabolic Engineering

scholarly journals Systems metabolic engineering: Genome-scale models and beyond

2010 ◽  
Vol 5 (7) ◽  
pp. 647-659 ◽  
Author(s):  
John Blazeck ◽  
Hal Alper
Keyword(s):  
Metabolic Engineering ◽  
Scale Models ◽  
Systems Metabolic Engineering ◽  
Genome Scale

Escherichia coli as a platform microbial host for systems metabolic engineering

2021 ◽  
Author(s):  
Dongsoo Yang ◽  
Cindy Pricilia Surya Prabowo ◽  
Hyunmin Eun ◽  
Seon Young Park ◽  
In Jin Cho ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Natural Products ◽  
Metabolic Engineering ◽  
Food Ingredients ◽  
E Coli ◽  
Renewable Biomass ◽  
Microbial Cell Factories ◽  
Cell Factories ◽  
Systems Metabolic Engineering ◽  
Microbial Host

Abstract Bio-based production of industrially important chemicals and materials from non-edible and renewable biomass has become increasingly important to resolve the urgent worldwide issues including climate change. Also, bio-based production, instead of chemical synthesis, of food ingredients and natural products has gained ever increasing interest for health benefits. Systems metabolic engineering allows more efficient development of microbial cell factories capable of sustainable, green, and human-friendly production of diverse chemicals and materials. Escherichia coli is unarguably the most widely employed host strain for the bio-based production of chemicals and materials. In the present paper, we review the tools and strategies employed for systems metabolic engineering of E. coli. Next, representative examples and strategies for the production of chemicals including biofuels, bulk and specialty chemicals, and natural products are discussed, followed by discussion on materials including polyhydroxyalkanoates (PHAs), proteins, and nanomaterials. Lastly, future perspectives and challenges remaining for systems metabolic engineering of E. coli are discussed.

Systems Metabolic Engineering Strategies: Integrating Systems and Synthetic Biology with Metabolic Engineering

2019 ◽  
Vol 37 (8) ◽  
pp. 817-837 ◽  
Author(s):  
Kyeong Rok Choi ◽  
Woo Dae Jang ◽  
Dongsoo Yang ◽  
Jae Sung Cho ◽  
Dahyeon Park ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Synthetic Biology ◽  
Systems Metabolic Engineering

Systems Metabolic Engineering Strategies for Non‐Natural Microbial Polyester Production

2019 ◽  
Vol 14 (9) ◽  
pp. 1800426 ◽  
Author(s):  
Youngjoon Lee ◽  
In J. Cho ◽  
So Y. Choi ◽  
Sang Y. Lee
Keyword(s):  
Metabolic Engineering ◽  
Systems Metabolic Engineering
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