Development and validation of a sensitive method for simultaneous determination of rosuvastatin andN-desmethyl rosuvastatin in human plasma using liquid chromatography/negative electrospray ionization/tandem mass spectrometry

2013 ◽  
Vol 27 (11) ◽  
pp. 1369-1374 ◽  
Author(s):  
H. K. Lee ◽  
C. S. Ho ◽  
M. Hu ◽  
B. Tomlinson ◽  
C. K. Wong
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Electrospray Ionization ◽  
Tandem Mass ◽  
Negative Electrospray Ionization ◽  
Development And Validation ◽  
Sensitive Method ◽  
Ionization Tandem Mass Spectrometry

Determination of parabens in human urine by liquid chromatography coupled with electrospray ionization tandem mass spectrometry

2014 ◽  
Vol 6 (15) ◽  
pp. 5566-5572 ◽  
Author(s):  
Shaoyou Lu ◽  
Shihan Gong ◽  
Shengtao Ma ◽  
Xiangying Zeng ◽  
Zhiqiang Yu ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Electrospray Ionization ◽  
Human Urine ◽  
Tandem Mass ◽  
Methyl Ethyl ◽  
Sensitive Method ◽  
Ionization Tandem Mass Spectrometry

A simple and sensitive method was developed for the simultaneous determination of methyl, ethyl,n-propyl,n-butyl, and benzyl parabens in human urine by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS).

Development and validation of a method for the determination of nicotinic acid in human plasma using liquid chromatography-negative electrospray ionization tandem mass spectrometry and its application to a bioequivalence study

2014 ◽  
Vol 6 (20) ◽  
pp. 8258-8267 ◽  
Author(s):  
Wei-Hua Huang ◽  
Kai Hu ◽  
Li Shao ◽  
Yao Chen ◽  
Wei Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Tandem Mass Spectrometry ◽  
Nicotinic Acid ◽  
Bioequivalence Study ◽  
Tandem Mass ◽  
Negative Electrospray Ionization ◽  
Development And Validation ◽  
Ionization Tandem Mass Spectrometry

For 60 years, nicotinic acid (NA) has been used as a potent vitamin in milligram doses while NA in gram doses has been administrated as a broad-spectrum lipid drug potent.

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