scholarly journals Comparison of time‐gated surface‐enhanced raman spectroscopy (TG‐SERS) and classical SERS based monitoring of Escherichia coli cultivation samples

2018 ◽  
Vol 34 (6) ◽  
pp. 1533-1542 ◽  
Author(s):  
Martin Kögler ◽  
Andrea Paul ◽  
Emmanuel Anane ◽  
Mario Birkholz ◽  
Alex Bunker ◽  
...  
The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3201-3209 ◽  
Author(s):  
Sachin K. Srivastava ◽  
Hilla Ben Hamo ◽  
Ariel Kushmaro ◽  
Robert S. Marks ◽  
Christoph Grüner ◽  
...  

A nanobiosensor chip, utilizing surface enhanced Raman spectroscopy on nanosculptured thin films of silver, was shown to detectEscherichia colibacteria down to the concentration level of a single bacterium.


The Analyst ◽  
2016 ◽  
Vol 141 (4) ◽  
pp. 1356-1362 ◽  
Author(s):  
Panxue Wang ◽  
Shintaro Pang ◽  
Juhong Chen ◽  
Lynne McLandsborough ◽  
Sam R. Nugen ◽  
...  

Here we presented a simple, rapid and label-free surface-enhanced Raman spectroscopy (SERS) based mapping method for the detection and discrimination ofSalmonella entericaandEscherichia coli onsilver dendrites.


2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.


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