In Situ Fluorescence Microscopy Study of the Interfacial Inhomogeneity of DNA Mixed Self-Assembled Monolayers at Gold Electrodes

2015 ◽  
Vol 2 (3) ◽  
pp. 434-442 ◽  
Author(s):  
Anne Meunier ◽  
Eleonore Triffaux ◽  
Dan Bizzotto ◽  
Claudine Buess-Herman ◽  
Thomas Doneux
Keyword(s):  
Fluorescence Microscopy ◽  
Microscopy Study ◽  
Self Assembled Monolayers ◽  
Gold Electrodes ◽  
Assembled Monolayers ◽  
Self Assembled

scholarly journals Localized dealloying corrosion mediated by self-assembled monolayers used as an inhibitor system

2015 ◽  
Vol 180 ◽  
pp. 191-204 ◽  
Author(s):  
B. R. Shrestha ◽  
A. Bashir ◽  
G. N. Ankah ◽  
M. Valtiner ◽  
F. U. Renner
Keyword(s):  
Microscopy Study ◽  
Structural Defects ◽  
Self Assembled Monolayers ◽  
Contact Printing ◽  
Local Composition ◽  
Force Microscopy ◽  
Assembled Monolayers ◽  
Inhibitor System ◽  
Self Assembled

The structure and chemistry of thiol or selenol self-assembled organic monolayers have been frequently addressed due to the unique opportunities in functionalization of materials. Such organic films can also act as effective inhibition layers to mitigate oxidation or corrosion. Cu–Au alloy substrates covered by self-assembled monolayers show a different dealloying mechanism compared to bare surfaces. The organic surface layer inhibits dealloying of noble metal alloys by a suppression of surface diffusion at lower potentials but at higher applied potentials dealloying proceeds in localized regions due to passivity breakdown. We present an in situ atomic force microscopy study of a patterned thiol layer applied on Cu–Au alloy surfaces and further explore approaches to change the local composition of the surface layers by exchange of molecules. The pattern for the in situ experiment has been applied by micro-contact printing. This allows the study of corrosion protection with its dependence on different molecule densities at different sites. Low-density thiol areas surrounding the high-density patterns are completely protected and initiation of dealloying proceeds only along the areas with the lowest inhibitor concentration. Dealloying patterns are highly influenced and controlled by molecular thiol to selenol exchange and are also affected by introducing structural defects such as scratches or polishing defects.

Electrochemical Release of Immobilized IgG Protein

2007 ◽  
Vol 1010 ◽  
Author(s):  
Tanveer Mahmud ◽  
Wojtek Wlodarski ◽  
Arnan Mitchell ◽  
Sally Gras ◽  
Adrian Trinchi ◽  
...  
Keyword(s):  
Fluorescence Microscopy ◽  
Self Assembled Monolayers ◽  
Protein Molecules ◽  
Reductive Desorption ◽  
Assembled Monolayers ◽  
Self Assembled ◽  
Coated Surfaces ◽  
Phosphate Buffered Saline ◽  
Covalent Interactions ◽  
Programmed Release

AbstractIn this paper, we present the electrochemically programmed release of immobilized IgG protein molecules that have been attached to gold coated surfaces via a thiol-gold linkage. Fluorescence microscopy has been used to image the release of fluorescently tagged IgGs in phosphate buffered saline. In this technique, the reductive desorption of self-assembled monolayers is employed for the release of proteins, which are immobilized on the surface either by non-covalent or covalent interactions. The voltage applied for the release of proteins is in a range of -1.5V to -60V.

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