scholarly journals Tetra-Aza-Pentacenes by means of a One-Pot Friedländer Synthesis

2018 ◽  
Vol 25 (6) ◽  
pp. 1472-1475 ◽  
Author(s):  
Narcisse Ukwitegetse ◽  
Patrick J. G. Saris ◽  
Jonathan R. Sommer ◽  
Ralf M. Haiges ◽  
Peter I. Djurovich ◽  
...  
2010 ◽  
Vol 345 (14) ◽  
pp. 1988-1997 ◽  
Author(s):  
Subbiah Nagarajan ◽  
Pandian Arjun ◽  
Nanjian Raaman ◽  
Thangamuthu Mohan Das

RSC Advances ◽  
2017 ◽  
Vol 7 (31) ◽  
pp. 18874-18882 ◽  
Author(s):  
Garima Singh ◽  
Srinivasarao Yaragorla

Highly efficient and regioselective Friedlander synthesis of 2-methyl-3-acyl quinolines and their chemoselective Csp3–H functionalization is described for the first time using Ca(OTf)2 as the sustainable catalyst under solvent free conditions with atom and step economy.


2008 ◽  
Vol 2008 (12) ◽  
pp. 679-682 ◽  
Author(s):  
P. Prabhakar Reddy ◽  
B. China Raju ◽  
J. Madhusudana Rao

2019 ◽  
Vol 16 (1) ◽  
pp. 154-159 ◽  
Author(s):  
Anchal Singhal ◽  
Pratibha Kumari ◽  
Kharu Nisa

Background: Quinolines represent an important class of bioactive molecules which are present in various synthetic drugs, biologically active natural compounds and pharmaceuticals. Quinolines find their potential applications in various chemical and biomedical fields. Thereby, the demand for more efficient and simple methodologies for the synthesis of quinolines is growing rapidly. </P><P> Objective: The green one-pot Friedlander Synthesis of Functionalized Quinolines has been demonstrated by using graphene oxide as a carbocatalyst. </P><P> Method: The graphene oxide catalyzed condensation reaction of 2–aminoaryl carbonyl compounds with different cyclic/ acyclic/ aromatic carbonyl compounds in methanol at 70°C affords different quinoline derivatives. </P><P> Results: The reaction has been examined in different protic and aprotic solvents and the best yield of quinoline is observed in methanol at 70°C. Conclusion: The present method of quinoline synthesis offers various advantages over other reported methods such as short reaction time, high yield of product, recycling of catalyst and simple separation procedure. The graphene oxide carbocatalyst can be easily recovered from the reaction mixture by centrifugation and then can be reused several times without any significant loss in its activity.


2020 ◽  
Author(s):  
José Tiago Menezes Correia ◽  
Gustavo Piva da Silva ◽  
Camila Menezes Kisukuri ◽  
Elias André ◽  
Bruno Pires ◽  
...  

A metal- and catalyst-free photoinduced radical cascade hydroalkylation of 1,7-enynes has been disclosed. The process is triggered by a SET event involving a photoexcited electron-donor-aceptor complex between NHPI ester and Hantzsch ester, which decomposes to afford a tertiary radical that is readily trapped by the enyne. <a>The method provides an operationally simple, robust and step-economical approach to the construction of diversely functionalized dihydroquinolinones bearing quaternary-centers. A sequential one-pot hydroalkylation-isomerization approach is also allowed giving access to a family of quinolinones. A wide substrate scope and high functional group tolerance was observed in both approaches</a>.


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