ChemInform Abstract: KINETICS OF THE HYDROXIDE ION CATALYZED DEALDOLIZATION OF DIACETONE ALCOHOL AT NORMAL AND HIGH PRESSURE

1979 ◽  
Vol 10 (50) ◽  
Author(s):  
F. GROENLUND ◽  
B. ANDERSEN
Keyword(s):  
High Pressure ◽  
Hydroxide Ion ◽  
Diacetone Alcohol ◽  
Kinetics Of

scholarly journals Kinetics of the Hydroxide Ion Catalyzed Dealdolization of Diacetone Alcohol at Normal and High Pressure.

1979 ◽  
Vol 33a ◽  
pp. 329-334 ◽  
Author(s):  
Finn Grønlund ◽  
Bjørn Andersen ◽  
Trond Rakke ◽  
Arne F. Andresen ◽  
Eberhard Hoyer ◽  
...  
Keyword(s):  
High Pressure ◽  
Hydroxide Ion ◽  
Diacetone Alcohol ◽  
Kinetics Of

Kinetics of the Imidazolium Ring-Opening of mRNA 5'-cap Analogs in Aqueous Alkali

2006 ◽  
Vol 71 (4) ◽  
pp. 567-578 ◽  
Author(s):  
Alicja Stachelska ◽  
Zbigniew J. Wieczorek ◽  
Janusz Stępiński ◽  
Marzena Jankowska-Anyszka ◽  
Harri Lönnberg ◽  
...  
Keyword(s):  
Electrostatic Interaction ◽  
Ring Opening ◽  
Nucleophilic Attack ◽  
Amino Groups ◽  
Hydroxide Ion ◽  
Methyl Group ◽  
Structural Modifications ◽  
Alkyl Groups ◽  
Imidazolium Ring ◽  
Kinetics Of

Second-order rate constants for the hydroxide-ion-catalyzed imidazolium ring-opening of several mono- and dinucleosidic analogs of mRNA 5'-cap have been determined. Intramolecular stacking of the two nucleobases in the dinucleosidic analogs, m7GpppN (m7G = 7-methylguanosine, N = 5'-linked nucleoside), and electrostatic interaction between the N-alkylated imidazolium ring and phosphate moiety have been shown to shield the m7G moiety against the nucleophilic attack of hydroxide ion. In addition, the effect of methylation of the nucleobase amino groups and replacement of the 7-methyl group with other alkyl groups have been studied. The influence of all the structural modifications studied turned out to be modest, the cleavage rates of the most and least reactive analogs (with the exception of non-phosphorylated nucleosides) differing only by a factor of 5.

The Diacetone Alcohol—Hydroxide Ion Reaction from the Standpoint of Ion-Dipole Theory

1944 ◽  
Vol 66 (11) ◽  
pp. 1823-1826 ◽  
Author(s):  
Edward S. Amis ◽  
George Jaffé ◽  
Ralph Theodore Overman
Keyword(s):  
Hydroxide Ion ◽  
Diacetone Alcohol

Kinetics of Chlorambucil Hydrolysis Using High-Pressure Liquid Chromatography

1982 ◽  
Vol 71 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Dulal C. Chatterji ◽  
Russell L. Yeager ◽  
Joseph F. Gallelli
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
High Pressure Liquid Chromatography ◽  
Kinetics Of
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