ChemInform Abstract: Studies of Organosulfur Compounds. Part 6. A Simple Method for Synthesis of Thieno(3,2-c)thiopyran Involving an Unusual Oxidation Under Mild Conditions.

The reactivity of N-thiophthalimides with silyl chalcogenides is described. Treatment of N-thiophthalimides with bis(trimethylsilyl) sulfide [(Me3Si)2S] leads to the formation of a mixture of the corresponding disulfides and trisulfides. On the other hand, N-thiophthalimides react with bis(trimethylsilyl) selenide [(Me3Si)2Se] under TBAF catalysis to smoothly give variously substituted diaryl, divinyl, and dialkyl disulfides; formation of a selenotrisulfide (dithiaselane, RSSeSR) is rationalized as an intermediate. Exploiting the different chemical behavior of silyl chalcogenides, we have disclosed a novel, selective, and operationally simple method to access disulfides in good yields under mild conditions.

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A Simple Method of Cyclization of the 2'-Hydroxychalcone with Polystyrene-Pyridine Resine under Mild Conditions

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.295-297.1156 ◽

2011 ◽

Vol 295-297 ◽

pp. 1156-1159

Author(s):

Xu Xu Zheng ◽

Jing Jing Xie ◽

Zhong Yi Yin ◽

Jia Jia Jing

Keyword(s):

Simple Method ◽

Chalcone Derivatives ◽

Mild Conditions ◽

Electron Group

The satisfying cyclization of 2’-hydroxy chalcone to flavanone using polystyrene-pyridine resine as catalyst and methanol as solvent under mild conditions is reported here. The method is appropriate for 2’-hydroxy chalcone derivatives with electron group in B-ring.

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Copper-Catalyzed Alkynylation of Benzylic C–H Bonds with Alkynylboronic Esters

Synlett ◽

10.1055/s-0040-1720474 ◽

2021 ◽

Author(s):

Søren Kramer ◽

Mikkel B. Buendia ◽

Jan-Georges J. Balin ◽

Mette E. Andersen ◽

Zhong Lian

Keyword(s):

Catalytic System ◽

Simple Method ◽

Mild Conditions

AbstractWe report a simple method for copper-catalyzed benzylic C–H alkynylation that uses alkynylboronic esters as nucleophilic coupling partners. The catalytic system is readily available and the reaction takes place under mild conditions. Different substrates for the C–H functionalization, as well as various alkynylboronic ester nucleophiles, were evaluated. Finally, three examples of enantioselective C–H alkynylations are presented.

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A clean and simple method for deprotection of phosphines from borane complexes

Pure and Applied Chemistry ◽

10.1515/pac-2017-0313 ◽

2018 ◽

Vol 90 (1) ◽

pp. 49-62 ◽

Cited By ~ 1

Author(s):

Oleg M. Demchuk ◽

Radomir Jasinski ◽

Dorota Strzelecka ◽

Kamil Dziuba ◽

Karolina Kula ◽

...

Keyword(s):

Functional Groups ◽

Phosphorus Atom ◽

Kinetic Data ◽

Reaction Conditions ◽

Simple Method ◽

Mild Conditions ◽

Excellent Yield ◽

Tertiary Phosphines ◽

Quantumchemical Calculations ◽

First Time

AbstractSimple, efficient, clean, and stereospecific protocols of protection of phosphorus atom with borane and deprotection from the borane complexes of the tertiary phosphines in mild conditions are reported. The proposed protection/deprotection reactions tolerate a range of functional groups and lead to pure products with excellent yield with no need for application of chromatographic or crystallisation purification procedures. For the first time mechanisms of the reactions of phosphine protection and deprotection have been studied based on experimental kinetic data as well as quantumchemical calculations, which allows designing reaction conditions suitable for a given substrate.

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Oxidative conversion of glucose to gluconic acid by iron(iii) chloride in water under mild conditions

Green Chemistry ◽

10.1039/c5gc02614h ◽

2016 ◽

Vol 18 (8) ◽

pp. 2308-2312 ◽

Cited By ~ 24

Author(s):

Hongdan Zhang ◽

Ning Li ◽

Xuejun Pan ◽

Shubin Wu ◽

Jun Xie

Keyword(s):

Gluconic Acid ◽

Oxidative Conversion ◽

Simple Method ◽

Mild Conditions

A simple method to oxidize glucose into gluconic acid in a concentrated FeCl3 solution under mild conditions was developed.

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Synthesis of novel quantum dots from DNA under mild conditions and their use as a fluorescent probe for the detection of Fe3+ and in biological imaging

Analytical Methods ◽

10.1039/c5ay01151e ◽

2015 ◽

Vol 7 (15) ◽

pp. 6274-6279 ◽

Cited By ~ 7

Author(s):

Guifang Cheng ◽

Weibo Zhang ◽

Ying Zhou ◽

Qifeng Ge ◽

Chaobiao Huang

Keyword(s):

Aqueous Solution ◽

Quantum Dots ◽

Fluorescent Probe ◽

Biological Imaging ◽

Water Soluble ◽

Iron Ions ◽

Simple Method ◽

Mild Conditions

We have demonstrated a simple method for the synthesis of water-soluble and well-dispersed fluorescent DNA-dots under mild conditions, which could be used as an effective fluorescent probe for the detection of iron ions with relatively good selectivity and sensitivity in an aqueous solution as well as in biological imaging applications.

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A Rapid and Simple Method for Quantitative Aziridination from Aminobrominated Derivatives of Olefins under Solvent-free and Mild Conditions

Chinese Journal of Chemistry ◽

10.1002/cjoc.201100176 ◽

2012 ◽

Vol 30 (2) ◽

pp. 391-399 ◽

Cited By ~ 8

Author(s):

Junfa Wei ◽

Zhanguo Chen ◽

Yanni Gao ◽

Peng Zhang ◽

Chuanning Wang ◽

...

Keyword(s):

Solvent Free ◽

Simple Method ◽

Mild Conditions ◽

Derivatives Of

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Alkoxymethylcyclosiloxanes - new efficient precursors of crystalline (CH3SiO3/2)8 silsesquioxane and polymethyl silsesquioxanes

e-Polymers ◽

10.1515/epoly.2008.8.1.1726 ◽

2008 ◽

Vol 8 (1) ◽

Author(s):

Anna Kowalewska ◽

Krystyna Rózga-Wijas ◽

Mirosław Handke

Keyword(s):

Solvent Effect ◽

Room Temperature ◽

Condensation Process ◽

Simple Method ◽

Hydrolytic Condensation ◽

Mild Conditions ◽

Highly Efficient ◽

Tetrabutylammonium Fluoride ◽

Substantial Degree

AbstractA new, highly efficient and very simple method for the synthesis of pure octahedral methylsilsesquioxanes (CH3SiO3/2)8, from cyclic 2,4,6,8-tetraalkoxy- 2,4,6,8-tetramethylsiloxane, was developed. We have found that T8Me can be synthesized from a mixture of alkoxymethylcyclosiloxane isomers in the hydrolytic condensation process, utilizing an ionic catalyst - tetrabutylammonium fluoride (TBAF). The reaction was carried out under very mild conditions, at room temperature, in a variety of solvents of different polarity. A substantial solvent effect was observed. THF helped in the formation of pure T8Me, whereas in other solvents mixtures of T8Me and poly(methylsilsesquioxanes) (PMQS) of substantial degree of regularity, were obtained.

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