ChemInform Abstract: Molecular Recognition and Chemical Reactions in Lattice Inclusion Complexes of the Natural Product Gossypol

ChemInform ◽  
2010 ◽  
Vol 27 (38) ◽  
pp. no-no
Author(s):  
B. IBRAGIMOV ◽  
S. TALIPOV
Keyword(s):  
Molecular Recognition ◽  
Natural Product ◽  
Inclusion Complexes ◽  
Chemical Reactions

Name Reactions: Strategies in Design of Chemodosimeters for Analyte Detection

2021 ◽  
Author(s):  
Ajit Kumar Mahapatra ◽  
Anwesha Maiti ◽  
Saikat Kumar Manna ◽  
Dipanjan Banik
Keyword(s):  
Molecular Recognition ◽  
Chemical Reactions ◽  
Design And Synthesis ◽  
Analyte Detection

Design and synthesis of suitable chemodosimeters for detection of toxic analytes has become challenging for new researchers nowadays in the molecular recognition field. Among different chemical reactions, name reaction-based approaches...

Inclusion complexes of the natural product gossypol

1994 ◽  
Vol 3 (2) ◽  
pp. 147-165 ◽  
Author(s):  
B. T. Ibragimov ◽  
S. A. Talipov ◽  
P. M. Zorky
Keyword(s):  
Natural Product ◽  
Inclusion Complexes

scholarly journals Solvent Derived Artifacts in Natural Products Chemistry

2009 ◽  
Vol 4 (3) ◽  
pp. 1934578X0900400 ◽  
Author(s):  
Federica Maltese ◽  
Frank van der Kooy ◽  
Robert Verpoorte
Keyword(s):  
Natural Products ◽  
Natural Product ◽  
Chemical Reactions ◽  
Critical Role ◽  
Total Yield ◽  
Purification Method ◽  
Active Compounds ◽  
Natural Product Chemistry ◽  
Extraction And Purification ◽  
Product Chemistry

Solvents play an important and critical role in natural product chemistry. They are mainly used during the extraction and purification of metabolites from a biological matrix. To a lesser extent, solvents are also used as reagents or catalysts to perform chemical reactions. This review focuses on the most important classes of solvents, including alcohols, halogen-containing solvents, esters, ethers, acids and bases. The chemical reactions associated with the use of these solvents to form the so-called “artifacts” are discussed and the most common contaminants found in these solvents are also reviewed. The formation of artifacts and the use of contaminated solvents mainly leads to the formation of new compounds, loss of activity of active compounds, formation of active compounds from inactive ones (false positives), loss in total yield of important compounds during isolation, formation of toxic compounds and difficulty in reproducing an extraction or purification method. Finally, the need for stability studies of purified natural products is emphasized, as this is a common overlooked aspect in natural product chemistry.

scholarly journals Molecular Recognition by Pillar[5]arenes: Evidence for Simultaneous Electrostatic and Hydrophobic Interactions

Pharmaceutics ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 60
Author(s):  
Borja Gómez-González ◽  
Luis García-Río ◽  
Nuno Basílio ◽  
Juan C. Mejuto ◽  
Jesus Simal-Gandara
Keyword(s):  
Molecular Recognition ◽  
Inclusion Complexes ◽  
Electrostatic Interactions ◽  
Alkyl Chain ◽  
Hydrophobic Interactions ◽  
Binding Constants ◽  
Ionic Interactions ◽  
Hydrophobic Effects ◽  
Hydrophobic Character ◽  
Electrostatic And Hydrophobic Interactions

The formation of inclusion complexes between alkylsulfonate guests and a cationic pillar[5]arene receptor in water was investigated by NMR and ITC techniques. The results show the formation of host-guest complexes stabilized by electrostatic interactions and hydrophobic effects with binding constants of up to 107 M−1 for the guest with higher hydrophobic character. Structurally, the alkyl chain of the guest is included in the hydrophobic aromatic cavity of the macrocycle while the sulfonate groups are held in the multicationic portal by ionic interactions.

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