Structure and Stability of Endohedral Complexes X@(HBNH)12.

ChemInform ◽  
2007 ◽  
Vol 38 (4) ◽  
Author(s):  
Hong Wang ◽  
Jian-Feng Jia ◽  
Hai-Shun Wu
Keyword(s):  
Structure And Stability ◽  
Endohedral Complexes

Structure and stability of endohedral complexes 4/2X@(HAlNH)2 (X = N, P, As, C−, Si−)

2011 ◽  
Vol 52 (1) ◽  
pp. 35-41
Author(s):  
C. -Yu. Zhang ◽  
X. Zhao ◽  
J. Zhang ◽  
B. -Q. Wang
Keyword(s):  
Structure And Stability ◽  
Endohedral Complexes

Structure and Stability of Endohedral Complexes X@B12P12

2005 ◽  
Vol 21 (05) ◽  
pp. 479-484
Author(s):  
WU Hai-Shun ◽  
◽  
◽  
ZHANG Zhu-Xia
Keyword(s):  
Structure And Stability ◽  
Endohedral Complexes

Structure and Stability of Endohedral Complexes X@(HAlNH)12 (X=Be,Mg, Ca, Zn, Al+, Ga+)

2008 ◽  
Vol 24 (03) ◽  
pp. 405-410
Author(s):  
ZHANG Cai-Yun ◽  
◽  
◽  
CUI Li-Ya ◽  
WU Hai-Shun
Keyword(s):  
Structure And Stability ◽  
Endohedral Complexes

Structure and Stability of Endohedral Complexes X@(HBNH)12

2006 ◽  
Vol 24 (11) ◽  
pp. 1509-1513 ◽  
Author(s):  
Hong Wang ◽  
Jian-Feng Jia ◽  
Hai-Shun Wu
Keyword(s):  
Structure And Stability ◽  
Endohedral Complexes

The Relation Between Polyhedral Borane Sandwiches and Endohedral Complexes; the Electronic Structure and Stability of X@YmBnHn+mq (X = He, Ne, Li, Be; Y = B, C, Si; m = 0-3; n = 12-9; q = -2 to +2), (C2B4H6)2Xq (X = Li, Al, Si; q = -3, -1, 0) and X2@B17H17q (X = He, Li; q = -2, 0)

2002 ◽  
Vol 67 (7) ◽  
pp. 965-990 ◽  
Author(s):  
Eluvathingal D. Jemmis ◽  
Elambalassery G. Jayasree
Keyword(s):  
Electronic Structure ◽  
Central Atom ◽  
Molecular Orbitals ◽  
Sandwich Complexes ◽  
Structure And Stability ◽  
Endohedral Complexes ◽  
Torsional Strain ◽  
Structural Connection

An electronic structural connection is established for sandwich complexes and polyhedral boranes containing encapsulated atoms. The charge requirements of these extreme geometrical patterns, examples 3 and 9, depend on the size of the central atom or on the distance between the adjacent rings. While going from the endohedral to the corresponding sandwich complexes the unoccupied a2u and eg molecular orbitals are stabilized considerably requiring additional 6 electrons for stability. The two endohedral atoms in the doped structures 10 resulting from the multidecker sandwich complexes 4 are found to stabilize the large borane skeleton. The energetics and geometries of the relatively less explored endohedral boranes show that endohedral silaboranes are more stable than the endohedral carbaboranes. In general, when an atom is encapsulated in a borane cage, its skeletal bonds are elongated. The exo bonds are shortened due to the possible reduction in the torsional strain between the adjacent vertices. A comparison of the endohedral complexes with the corresponding exo isomers shows that encapsulation makes the system more strained.

Polyplex: A Promising Gene Delivery System

2019 ◽  
Vol 12 (6) ◽  
pp. 4681-4686
Author(s):  
Rohan Aggarwal ◽  
Monika Targhotra ◽  
Bhumika Kumar ◽  
P.K Sahoo ◽  
Meenakshi K Chauhan
Keyword(s):  
Gene Transfer ◽  
Gene Delivery ◽  
Delivery System ◽  
Viral Vectors ◽  
Gene Delivery System ◽  
Cationic Polymers ◽  
Therapeutic Application ◽  
Promising Alternative ◽  
Structure And Stability ◽  
The Past

In the past few years gene delivery system has gained a huge attention owing to its proved efficacy in several diseases especially in those caused by genetic and/oroncological malfunctioning. The effective gene delivery mainly depends on the carrier molecules that can ensure the safe and specific delivery of the nucleic acidmolecules. Viral vectors have been used for a longer period as the gene transfer vehicle. However, these viral vectors have potential immunological disadvantages that made them less preferred. Recently, non-viral vectors such as polyplexes have emerged as a promising alternative for viral vectors. Polyplexes are formed by conjugating a polymer with DNA and in maximum cases the cationic polymers are preferred over others. The structure and stability of the polyplexes depends on various factors. The ability of the polymer to condense the DNA mainly dictates the efficiency of the polyplex mediated transfection. In this review we are going to provide a framework for the synthesis and design of the polyplexes along with the structure and stability of the complexes pertaining to mechanism of action, characterization and therapeutic application, including polyethyleneimine mediated cytotoxicity as well as newer strategies for the generation of better polyplexes.

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