Synthesis of the β-keto acids from benzimidazolium iodides and ethyl malonate

2010 ◽  
Vol 18 (6) ◽  
pp. 940-941 ◽  
Author(s):  
Zhen Shi ◽  
Jin-Yuan Ta
Keyword(s):  
1961 ◽  
Vol 26 (1) ◽  
pp. 141-155 ◽  
Author(s):  
S. Ono ◽  
M. Takagi ◽  
T. Wasa
Keyword(s):  

1986 ◽  
Vol 51 (12) ◽  
pp. 2781-2785 ◽  
Author(s):  
M. Martín Herrera ◽  
J. J. Maraver Puig ◽  
F. Sánchez Burgos

A study is made on the kinetic salt effect on the reaction of hydrolysis of several charged esters in alkaline media. The results are interpreted on the basis of the coulombic interaction, the salting in of hydroxide ion and a third component depending on size of the substrate.


1946 ◽  
Vol 165 (2) ◽  
pp. 741-742
Author(s):  
Jesse P. Greenstein ◽  
Charles E. Carter
Keyword(s):  

1971 ◽  
Vol 246 (23) ◽  
pp. 7241-7249
Author(s):  
Leonard A. Fahien ◽  
Jia-Huey Lin-Yu ◽  
Susannah E. Smith ◽  
John M. Happy

JACS Au ◽  
2021 ◽  
Author(s):  
Shibaji Basak ◽  
Serge Nader ◽  
Sheref S. Mansy
Keyword(s):  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
José C. Páez-Franco ◽  
Jiram Torres-Ruiz ◽  
Víctor A. Sosa-Hernández ◽  
Rodrigo Cervantes-Díaz ◽  
Sandra Romero-Ramírez ◽  
...  

AbstractWe identified the main changes in serum metabolites associated with severe (n = 46) and mild (n = 19) COVID-19 patients by gas chromatography coupled to mass spectrometry. The modified metabolic profiles were associated to an altered amino acid catabolism in hypoxic conditions. Noteworthy, three α-hydroxyl acids of amino acid origin increased with disease severity and correlated with altered oxygen saturation levels and clinical markers of lung damage. We hypothesize that the enzymatic conversion of α-keto-acids to α- hydroxyl-acids helps to maintain NAD recycling in patients with altered oxygen levels, highlighting the potential relevance of amino acid supplementation during SARS-CoV-2 infection.


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