Hollow Mesoporous Silica@Metal-Organic Framework and Applications for pH-Responsive Drug Delivery

ChemMedChem ◽  
2018 ◽  
Vol 13 (5) ◽  
pp. 400-405 ◽  
Author(s):  
Xiaomin Jia ◽  
Zhiyuan Yang ◽  
Yujun Wang ◽  
Ya Chen ◽  
Haitao Yuan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Metal Organic Framework ◽  
Ph Responsive ◽  
Metal Organic ◽  
Hollow Mesoporous Silica ◽  
Organic Framework

A versatile stimulus-responsive metal–organic framework for size/morphology tunable hollow mesoporous silica and pH-triggered drug delivery

2017 ◽  
Vol 5 (11) ◽  
pp. 2126-2132 ◽  
Author(s):  
Zhen Zou ◽  
Siqi Li ◽  
Dinggeng He ◽  
Xiaoxiao He ◽  
Kemin Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Metal Organic Framework ◽  
Three Dimensional ◽  
Ph Responsive ◽  
Intracellular Drug Delivery ◽  
Stimulus Responsive ◽  
Metal Organic ◽  
Hollow Mesoporous Silica ◽  
Pore Blocker

The ZIF-8 is applied for the preparation of size tunable three-dimensional hollow mesoporous silica materials (HMSNs) and used as a novel pore blocker for pH-responsive intracellular drug delivery system by grafting it onto the HMSN.

Coordination polymer nanocapsules prepared using metal–organic framework templates for pH-responsive drug delivery

2017 ◽  
Vol 28 (27) ◽  
pp. 275601 ◽  
Author(s):  
Lei Tang ◽  
Jiafu Shi ◽  
Xiaoli Wang ◽  
Shaohua Zhang ◽  
Hong Wu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Coordination Polymer ◽  
Metal Organic Framework ◽  
Ph Responsive ◽  
Metal Organic ◽  
Organic Framework

A Biocompatible Ti-based metal-organic framework for pH responsive drug delivery

2018 ◽  
Vol 225 ◽  
pp. 142-144 ◽  
Author(s):  
Ke Jiang ◽  
Ling Zhang ◽  
Quan Hu ◽  
Yanyu Yang ◽  
Wenxin Lin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Ph Responsive ◽  
Metal Organic ◽  
Organic Framework

scholarly journals Recent developments on zinc(ii) metal–organic framework nanocarriers for physiological pH-responsive drug delivery

MedChemComm ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 2038-2051 ◽  
Author(s):  
Weicong Liu ◽  
Ying Pan ◽  
Weiwei Xiao ◽  
Hongjia Xu ◽  
Dong Liu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Review Article ◽  
The Body ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Stimulus Responsive ◽  
Recent Developments ◽  
Metal Organic ◽  
Organic Framework

In this review article, we discuss the diverse stimuli achieved upon outside activation from single pH-stimulus-responsive or/and multiple pH-stimuli-responsive viewpoints in the body.

scholarly journals A combination of glioma in vivo imaging and in vivo drug delivery by metal–organic framework based composite nanoparticles

2019 ◽  
Vol 7 (48) ◽  
pp. 7683-7689 ◽  
Author(s):  
Yuan-Bo Pan ◽  
Siqi Wang ◽  
Xiuchao He ◽  
Weiwei Tang ◽  
Jianhua Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Loading Rate ◽  
Metal Organic Framework ◽  
Drug Loading ◽  
Composite Nanoparticles ◽  
Ph Responsive ◽  
Resonance Imaging ◽  
Metal Organic ◽  
Organic Framework

Metal–organic framework based composite nanoparticles (Mn-ZIF-8/5-Fu) was used for glioma treatment with high drug loading rate and pH responsive drug delivery capacity. Mn-ZIF-8/5-Fu demonstrated good magnetic resonance imaging capacity.

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